Guanine, Adenine, and Hypoxanthine Production in UV-Irradiated Formamide Solutions: Relaxation of the Requirements for Prebiotic Purine Nucleobase Formation (Articolo in rivista)

Type
Label
  • Guanine, Adenine, and Hypoxanthine Production in UV-Irradiated Formamide Solutions: Relaxation of the Requirements for Prebiotic Purine Nucleobase Formation (Articolo in rivista) (literal)
Anno
  • 2010-01-01T00:00:00+01:00 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi
  • 10.1002/cbic.201000074 (literal)
Alternative label
  • Barks, H.(a) , R. Buckley(a), G A. Grieves(a), E. Di Mauro (b) , N.Hud (a) and T. Orlando (a) (2010)
    Guanine, Adenine, and Hypoxanthine Production in UV-Irradiated Formamide Solutions: Relaxation of the Requirements for Prebiotic Purine Nucleobase Formation
    in ChemBioChem (Print); WILEY-V C H VERLAG GMBH, WEINHEIM (Germania)
    (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
  • Barks, H.(a) , R. Buckley(a), G A. Grieves(a), E. Di Mauro (b) , N.Hud (a) and T. Orlando (a) (literal)
Pagina inizio
  • 1240 (literal)
Pagina fine
  • 1243 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume
  • 11 (literal)
Rivista
Note
  • ISI Web of Science (WOS) (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
  • H. L. Barks ,+ R. Buckley,+ G. A. Grieves, Prof. N. V. Hud, Prof. T. M. Orlando School of Chemistry and Biochemistry Georgia Institute of Technology Atlanta, GA 30332-0400 (USA) Fax: (+1) 404-385-6057 E-mail: thomas.orlando@chemistry.gatech.edu hud@gatech.edu [b] E. Di Mauro Dipartimento di Genetica e Biologica Molecolare Universit? La Sapienza P. le Aldo Moro 5, 00185 Rome (Italy) (literal)
Titolo
  • Guanine, Adenine, and Hypoxanthine Production in UV-Irradiated Formamide Solutions: Relaxation of the Requirements for Prebiotic Purine Nucleobase Formation (literal)
Abstract
  • The RNA-world hypothesis has generated much interest in finding a plausible prebiotic route to RNA. The abiotic synthesis of the purine nucleobases is of particular interest, given proposals that early proto-RNA polymers might have contained only purine nucleobases. Formamide is attractive as a potential prebiotic starting material for the nucleobases; it contains the four required elements (C, H, O, N) and stands out because of its likely prebiotic availability, relative stability, versatile reactivity, and low volatility compared to water. (literal)
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