Design and Characterization of a Novel Fibre-reinforced Composite for Spinal Fusion (Abstract/Poster in atti di convegno)

Type
Label
  • Design and Characterization of a Novel Fibre-reinforced Composite for Spinal Fusion (Abstract/Poster in atti di convegno) (literal)
Anno
  • 2006-01-01T00:00:00+01:00 (literal)
Alternative label
  • L. Manto, A. Gloria, B. Esposito, R. De Santis, L. Ambrosio, L. Nicolais (2006)
    Design and Characterization of a Novel Fibre-reinforced Composite for Spinal Fusion
    in International Conference on Advances in Biomaterials for Drug Delivery and Regenerative Medicine, Capri
    (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
  • L. Manto, A. Gloria, B. Esposito, R. De Santis, L. Ambrosio, L. Nicolais (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#descrizioneSinteticaDelProdotto
  • Fusion is one of the major surgical methods for degenerative lumbar conditions. It means eliminating a motion segment between two adjacent vertebrae by the use of bone graft and sometimes by an internal fixation. The aim of this work was to manufacture a novel composite fusion device and to characterize its biomechanical behaviour through experimental and theoretical testing. Mechanical properties are assessed through a porcine model and compared to the properties of natural IVD and the properties of IVD prosthesized with a commercial titanium cage (SOFAMOR Danek). The PEI reinforced with carbon fibres cage has shown interesting mechanical properties. Such as titanium-based segments, the IVDs prosthesized by employing the fibre-reinforced PEI-based cage have presented a maximum strain value which is about two orders of magnitude smaller compared to healthy L4-L5; the effect of the cage is the reduction of relative movements between the two adjacent vertebrae. However, differently from systems with commercial titanium device, the IVD prosthesized with the novel composite cage has shown a Young’s modulus closer to the natural IVD. Therefore, through a suitable composite cage design it is possible to control stress-strain distributions and hence the mechanical signals to bone, thus avoiding the stress-shielding phenomena, which is typical of the metallic prostheses and causes bone resorption. (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
  • Institute of Composite and Biomedical Materials, CNR and CRIB, University of Naples “Federico II”, P.le Tecchio 80, 80125 Naples, Italy (literal)
Titolo
  • Design and Characterization of a Novel Fibre-reinforced Composite for Spinal Fusion (literal)
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