http://www.cnr.it/ontology/cnr/individuo/prodotto/ID113521

Materials for Vertebral Arthroplasty: in vivo Biofunctionality studies of UHMWPE, Delrin and HAPEX (Abstract/Poster in atti di convegno)

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Materials for Vertebral Arthroplasty: in vivo Biofunctionality studies of UHMWPE, Delrin and HAPEX (Abstract/Poster in atti di convegno) (literal)

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E. Damien, KE Tanner, L Ambrosio, PA Revell (2005)
Materials for Vertebral Arthroplasty: in vivo Biofunctionality studies of UHMWPE, Delrin and HAPEX
in 19th European Conference on Biomaterials, Sorrento
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Low back pain is extremely common in today's society. 75 % of all people will experience back pain at some time in their lives. 30 million Americans have LBP at any given time. The cost of annual health care is estimated to be over Billion. The aim of this study was to investigate the histological responses to intraosseously implanted bioinert ultra high molecular weight polyethylene (UHMWPE), polyoxymethylene (Delrin), and hydroxyapatite-polyethylene (HA/PE), (HAPEX)) as possible materials for vertebral arthroplasty. Delrin, a thermoplastic polymer with creep resistance ten times that of UHMWPE, is clinically used as a material for sockets in total joint prostheses. The biofunctionality studies on UHMWPE, Delrin and HAPEX after 5 weeks of implantation indicated that HAPEX is the best promising candidate material for vertebral arthroplasty, although UHMWPE and Delrin are biocompatible. In vivo total disc replacement studies in large animals are underway. (literal)

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