http://www.cnr.it/ontology/cnr/individuo/prodotto/ID11334
One-pot TiO2-Catalyzed Synthesis of Nucleic Bases and Acyclonucleosides from Formamide: Implications for the Origin of Life (Articolo in rivista)
- Type
- Label
- One-pot TiO2-Catalyzed Synthesis of Nucleic Bases and Acyclonucleosides from Formamide: Implications for the Origin of Life (Articolo in rivista) (literal)
- Anno
- 2003-01-01T00:00:00+01:00 (literal)
- Alternative label
Saladino R. , Ciambecchini U. , Crestini C. , Costanzo G. , Negri R. , Di Mauro E. (2003)
One-pot TiO2-Catalyzed Synthesis of Nucleic Bases and Acyclonucleosides from Formamide: Implications for the Origin of Life
in ChemBioChem (Print)
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- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
- Saladino R. , Ciambecchini U. , Crestini C. , Costanzo G. , Negri R. , Di Mauro E. (literal)
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- E. Di Mauro è a disposizione dell'IBPM (literal)
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- ISI Web of Science (WOS) (literal)
- Titolo
- One-pot TiO2-Catalyzed Synthesis of Nucleic Bases and Acyclonucleosides from Formamide: Implications for the Origin of Life (literal)
- Abstract
- A novel one-pot TiO2-catalyzed synthesis of nucleobases and acyclonucleosides from formamide is reported. Being formamide a compound that can be formed under prebiotic conditions these reactions have implications for the origin of life. While a number of purine derivatives have been found in non-TiO2-catalyzed reactions, important compounds that would not otherwise occur (namely: thymine, 5-hydroxymethyluracil and acyclonucleosides)are formed in acceptable yields. Moreover, TiO2 selectively affects the rates of degradation of nucleobases, single and embedded in polynucleotides. (literal)
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