The use of surname and Y-chromosome analyses for reconstructing past population structure: the test case of Sardinia (Comunicazione a convegno)

Type
Label
  • The use of surname and Y-chromosome analyses for reconstructing past population structure: the test case of Sardinia (Comunicazione a convegno) (literal)
Anno
  • 2010-01-01T00:00:00+01:00 (literal)
Alternative label
  • Nici C, Grugni V, Crobu F, Battaglia V, Parolo S, l-Zahery N, Olivieri A, Fiorani O, Lisa A, Torroni A, Semino O (2010)
    The use of surname and Y-chromosome analyses for reconstructing past population structure: the test case of Sardinia
    in VI Congresso Nazionale di Arecheometria. Scienze e Beni Culturali., Pavia, 15-18 Febbraio 2010
    (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
  • Nici C, Grugni V, Crobu F, Battaglia V, Parolo S, l-Zahery N, Olivieri A, Fiorani O, Lisa A, Torroni A, Semino O (literal)
Pagina inizio
  • 59 (literal)
Pagina fine
  • 59 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
  • Dipartimenlo di Genetica e Microbiologa \"A. BuzzaliTraverso\", Università di Pavia; INN-CNR Cagliari; IGM-CNR, Pavia. (literal)
Titolo
  • The use of surname and Y-chromosome analyses for reconstructing past population structure: the test case of Sardinia (literal)
Abstract
  • The male specific region of the Y chromosome is uniparentally transmitted. It escapes recombination and its evolution is only due to the sequential accumulation of new mutations along radiating paternal lineages. Due to this process, which occurred mainly during and after the process of human colonization and diffiusion into the differentgeographic region, the present y-chromosome sequence variation represents a uniquerecord of the biological history of our species and mìdern populations. rts analysis allowsthe identification of ancestral and.founder haplotypes, thetdetection of ancient migrationroutes and the estimation of migration times. However, this analysis is sometimesundermined by recent migrations which became more and more important also for \"isolated\" populations, weakening the boundaries of genetic isolates by making uniform the distribution of genetic markers. A solution for this problem is represented by the reconstruction of the ancient isolates starting from the present data by using the information obtained from the surname analysis. With the aim of investigating the peopling of Sardinia and the aspects of its human Y-chromosome contemporary variation that can be ascribed to primary colonization, Neolithic dispersals or more recent everts of gene flow, we have analyzed in detail the Y-chromosome haplogroup distributions in a wide sample (more than 500 Y crhomosomes) whose surname origin could be attributed specifically to one of the different Sardinian linguistic zones. In addition, in order to evaluate the divergence of the different haplogroups observed in the island, and therefore theirc oalescent time, a set of 12 STR loci was examined. On the whole, by the comparison of 11 regions representative of ancient Sardinian isolates, a significaní differentiation has been confirmed for the central eastern area of the island, in agreement with historical and linguistic data that indicate this region as the \"archaic zone\". This is due to a lower incidence of haplogroups arrived in Europe during the Neolithic and post Neolithic times, but mainly to a significative higher frequency of the Paleolithic haplogroup I-M26. (literal)
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