The prognostic value of Doppler echocardiographic derived coronary flow reserve is not affected by concomitant anti-ischemic therapy at the time of testing (Abstract in rivista)

Type

• Prodotto della ricerca (Classe)
• Abstract in rivista (Classe)

Label

• The prognostic value of Doppler echocardiographic derived coronary flow reserve is not affected by concomitant anti-ischemic therapy at the time of testing (Abstract in rivista) (literal)

Anno

• 2007-01-01T00:00:00+01:00 (literal)

Alternative label

• Sicari R.; Rigo F.; Gherardi S.; Cortigiani L.; Gianfaldoni M. L.; Galderisi M.; Djordjevic-Dikic A.; Ossena G.; Picano E. (2007)
  The prognostic value of Doppler echocardiographic derived coronary flow reserve is not affected by concomitant anti-ischemic therapy at the time of testing
  in European Heart Journal, 2007
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• Sicari R.; Rigo F.; Gherardi S.; Cortigiani L.; Gianfaldoni M. L.; Galderisi M.; Djordjevic-Dikic A.; Ossena G.; Picano E. (literal)

Convegno

• European Heart Journal (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#note

• In: European Heart Journal, vol. 28 Oxford Journals, 2007. (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#descrizioneSinteticaDelProdotto

• Background: When wall motion abnormality is the diagnostic end-point, concomitant anti-ischemic therapy heavily modulates the prognostic value of dipyridamole echo test (DET). Coronary flow reserve (CFR) was added to wall motion in dual imaging DET. Aim: to determine whether antianginal medications affect the prognostic value of Doppler echocardiographic derived CFR in patients with known or suspected coronary artery disease undergoing DET. Methods: We evaluated 1506 patients (911 males; 64±11 years) who underwent high dose dipyridamole (0.84 mg/kg over 6') stress echo with CFR evaluation of LAD by Doppler. Six-hundred fifty eight (44%) patients were on antiischemic therapy at time of testing. Results: Mean CFR was 2.3.±0.6. During a median follow-up of 42 months, 74 events occurred: 24 deaths and 50 nonfatal myocardial infarctions. Survival was highest in 955 patients with normal (2.0) CFR and lowest in 951 patients with abnormal CFR (93% vs 63%, p= 0.0001). Concomitant therapy did not affect prognostic value of CFR (figure). At multivariable analysis, angina during DET (hazard ratio [HR] 2.6, 95% CI 1.6 - 4.4, P= .000), WMSI at peak stress (hazard ratio [HR] 2.2, 95% CI 1.2 - 3.9, P= .007), DET positivity for regional wall motion abnormalities (hazard ratio [HR] 6.4, 95% CI 3.5 - 11.7, P= .000), a CFR of LAD 2 (hazard ratio [HR] 2.4, 95% CI 1.4-4.1, P (literal)

Titolo

• The prognostic value of Doppler echocardiographic derived coronary flow reserve is not affected by concomitant anti-ischemic therapy at the time of testing (literal)

Prodotto di

• Echolab (ME.P01.007.001) (Modulo)
• Istituto di fisiologia clinica (IFC) (Istituto)

Autore CNR

• EUGENIO PICANO (Persona)
• ROSA SICARI (Unità di personale interno)

Insieme di parole chiave

• Parole chiave di "The prognostic value of Doppler echocardiographic derived coronary flow reserve is not affected by concomitant anti-ischemic therapy at the time of testing" (Insieme di parole chiave)

Incoming links:

Autore CNR di

• EUGENIO PICANO (Persona)
• ROSA SICARI (Unità di personale interno)

Prodotto

• Istituto di fisiologia clinica (IFC) (Istituto)
• Echolab (ME.P01.007.001) (Modulo)

Insieme di parole chiave di

• Parole chiave di "The prognostic value of Doppler echocardiographic derived coronary flow reserve is not affected by concomitant anti-ischemic therapy at the time of testing" (Insieme di parole chiave)