http://www.cnr.it/ontology/cnr/individuo/prodotto/ID10421
Incidental detection by [(11)C]choline PET/CT of meningiomas in prostate cancer patients (Articolo in rivista)
- Type
- Label
- Incidental detection by [(11)C]choline PET/CT of meningiomas in prostate cancer patients (Articolo in rivista) (literal)
- Anno
- 2009-01-01T00:00:00+01:00 (literal)
- Alternative label
Fallanca F. 1, Giovacchini G. 2, Picchio M. 1, Bettinardi V. 1, Messa C. 2,3,4, Fazio F. 1,2 (2009)
Incidental detection by [(11)C]choline PET/CT of meningiomas in prostate cancer patients
(literal)
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- Fallanca F. 1, Giovacchini G. 2, Picchio M. 1, Bettinardi V. 1, Messa C. 2,3,4, Fazio F. 1,2 (literal)
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- Pubblicato on-line: 13 Marzo 2009
Corresponding author: C. Messa (cmessa@hsgerardo.org).
IF 2009: 2.877 (literal)
- Note
- ISI Web of Science (WOS) (literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
- 1. UO di Medicina Nucleare, Istituto Scientifico Universitario S. Raffaele, Milano
2. Centro di Bioimmagini Molecolari, Università degli Studi di Milano-Bicocca.
3. Dipartimento di Medicina Nucleare, Ospedale S. Gerardo, Monza (MI)
4. IBFM-CNR, Segrate (MI) (literal)
- Titolo
- Incidental detection by [(11)C]choline PET/CT of meningiomas in prostate cancer patients (literal)
- Abstract
- AIM: Anti-androgenic hormonal therapy in prostate cancer patients with concomitant meningioma may result in tumor growth and development of neurological symptoms. Positron emission tomography/computed tomography (PET/CT) with [(11)C]choline is used for restaging prostate cancer patients with biochemical failure. In vitro and in vivo data support altered choline metabolism in meningiomas. METHODS: During a retrospective study in prostate cancer patients with biochemical failure referred to our institution between November 2004 and Ja-nuary 2007, encephalic focal uptake of [(11)C]choline was incidentally noted in 4 patients, 2 of which had been taking luteinizing hormone-releasing hormone analogs. RESULTS: Subsequent to the incidental finding, one patient underwent surgical removal of the meningioma; strict neuroradiological follow-up was planned for the 3 other patients. CONCLUSIONS: We suggest that in prostate cancer patients candidate for anti-androgenic therapy the whole body [(11)C]choline PET/CT scan should include the whole skull to check for the possible presence of meningiomas. This could help to identify patients at risk for the development of neurological symptoms during anti-androgenic therapy and help the referring urologist in the clinical management of these patients. (literal)
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