http://www.cnr.it/ontology/cnr/individuo/prodotto/ID10396
Negation in the brain: Modulating action representations (Articolo in rivista)
- Type
- Label
- Negation in the brain: Modulating action representations (Articolo in rivista) (literal)
- Anno
- 2008-01-01T00:00:00+01:00 (literal)
- Alternative label
Tettamanti M. 1,2,3, Manenti R. 2,4, Della Rosa P.A. 2,4, Falini A. 1,4, Perani D. 2,3,4,5, Cappa S.F. 2,3,4, Moro A. 2,4 (2008)
Negation in the brain: Modulating action representations
in NeuroImage (Orlando Fla., Print)
(literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
- Tettamanti M. 1,2,3, Manenti R. 2,4, Della Rosa P.A. 2,4, Falini A. 1,4, Perani D. 2,3,4,5, Cappa S.F. 2,3,4, Moro A. 2,4 (literal)
- Pagina inizio
- Pagina fine
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume
- Rivista
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#note
- Pubblicato on-line: 15 Agosto 2008.
Corresponding author: M. Tettamanti (tettamanti.marco@hsr.it).
I.F.: 5.694 (literal)
- Note
- ISI Web of Science (WOS) (literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
- 1. Scientific Institute San Raffaele, Milano
2. CERMAC-HSR, Milano
3. National Institute of Neuroscience, Torino
4. Vita-Salute San Raffaele University, Milano
5. Institute of Molecular Bioimaging and Physiology, CNR, Segrate (MI)
(literal)
- Titolo
- Negation in the brain: Modulating action representations (literal)
- Abstract
- Sentential negation is a universal syntactic feature of human languages that reverses the truth value expressed by a sentence. An intriguing question concerns what brain mechanisms underlie our ability to represent and understand the meaning of negative sentences. We approach this issue by investigating action-related language processing and the associated neural representations. Using functional magnetic resonance imaging we measured brain activity in 18 healthy subjects during passive listening of sentences characterized by a factorial combination of polarity (affirmative vs. negative) and concreteness (action-related vs. abstract). Negation deactivated cortical areas and the left pallidum. Compared to abstract sentences, action-related sentences activated the left-hemispheric action-representation system. Crucially, the polarity by concreteness interactions showed that the activity within the action-representation system was specifically reduced for negative action-related vs. affirmative action-related sentences (compared to abstract sentences). Accordingly, functional integration within this system as measured by Dynamic Causal Modeling was specifically weaker for negative action-related than for affirmative action-related sentences. This modulation of action representations indicates that sentential negation transiently reduces the access to mental representations of the negated information. (literal)
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