Evidence of limited motion of the prostate by carefully emptying the rectum as assessed by daily MVCT image guidance with helical tomotherapy. (Articolo in rivista)

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  • Evidence of limited motion of the prostate by carefully emptying the rectum as assessed by daily MVCT image guidance with helical tomotherapy. (Articolo in rivista) (literal)
Anno
  • 2008-01-01T00:00:00+01:00 (literal)
Alternative label
  • Fiorino C. 3, Di Muzio N. 1, Broggi S. 3, Cozzarini C. 1, Maggiulli E. 3, Alongi F. 1, Valdagni R. 2, Fazio F. 1,4, Calandrino R. 1 (2008)
    Evidence of limited motion of the prostate by carefully emptying the rectum as assessed by daily MVCT image guidance with helical tomotherapy.
    (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
  • Fiorino C. 3, Di Muzio N. 1, Broggi S. 3, Cozzarini C. 1, Maggiulli E. 3, Alongi F. 1, Valdagni R. 2, Fazio F. 1,4, Calandrino R. 1 (literal)
Pagina inizio
  • 611 (literal)
Pagina fine
  • 617 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume
  • 71 (literal)
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  • Corresponding author: Claudio Fiorino (fiorino.claudio@hsr.it) I.F.: 4.639 (literal)
Note
  • ISI Web of Science (WOS) (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
  • 1. Department of Radiotherapy, S. Raffaele Institute, Milan, Italy 2. Prostate Program, National Institute of Cancer, Milan, Italy 3. Medical Physics, S. Raffaele Institute, Milano, Italy 4. Istituto Bioimmagini e Fisiologia Molecolare, Consiglio Nazionale Richerche, Milan, Italy (literal)
Titolo
  • Evidence of limited motion of the prostate by carefully emptying the rectum as assessed by daily MVCT image guidance with helical tomotherapy. (literal)
Abstract
  • PURPOSE: To assess setup and organ motion error by means of analysis of daily megavoltage computed tomography (MVCT) of patients treated with hypofractionated helical tomotherapy (71.4-74.2 Gy in 28 fractions). METHODS AND MATERIALS: Data from 21 patients were analyzed. Patients were instructed to empty the rectum carefully before planning CT and every morning before therapy by means of a self-applied rectal enema. The position of the prostate was assessed by means of automatic bone matching (BM) with the planning kilovoltage CT (BM, setup error) followed by a direct visualization (DV) match on the prostate. Deviations between planning and therapy positions referred to BM and BM + DV were registered for the three main axes. In case of a full rectum at MVCT with evident shift of the prostate, treatment was postponed until after additional rectal emptying procedures; in this case, additional MVCT was performed before delivering the treatment. Data for 522 fractions were available; the impact of post-MVCT procedure was investigated for 17 of 21 patients (410 fractions). RESULTS: Prostate motion relative to bony anatomy was limited. Concerning posterior-anterior shifts, only 4.9% and 2.7% of fractions showed deviation of 3 mm or greater of the prostate relative to BM without and with consideration of post-MVCT procedures, respectively. Interobserver variability for BM + DV match was within 0.8 mm (1 SD). CONCLUSIONS: Daily MVCT-based correction is feasible. The BM + DV matching was found to be consistent between operators. Rectal emptying using a daily enema is an efficient tool to minimize prostate motion, even for centers that have not yet implemented image-guided radiotherapy. (literal)
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