http://www.cnr.it/ontology/cnr/individuo/prodotto/ID10319

Post-therapy surveillance of patients with uterine cancers: value of integrated FDG PET/CT in the detection of recurrence. (Articolo in rivista)

Type

Articolo in rivista (Classe)
Prodotto della ricerca (Classe)

Label

Post-therapy surveillance of patients with uterine cancers: value of integrated FDG PET/CT in the detection of recurrence. (Articolo in rivista) (literal)

Anno

2007-01-01T00:00:00+01:00 (literal)

Alternative label

Sironi S. 1,3, Picchio M. 4, Landoni C. 1,4, Galimberti S. 1,5, Signorelli M. 6, Bettinardi V. 4, Perego P. 7, Mangioni C. 1,6, Messa C. 1,2,8, Fazio F. 1,2,4 (2007)
Post-therapy surveillance of patients with uterine cancers: value of integrated FDG PET/CT in the detection of recurrence.
in European journal of nuclear medicine and molecular imaging (Print)
(literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

Sironi S. 1,3, Picchio M. 4, Landoni C. 1,4, Galimberti S. 1,5, Signorelli M. 6, Bettinardi V. 4, Perego P. 7, Mangioni C. 1,6, Messa C. 1,2,8, Fazio F. 1,2,4 (literal)

Pagina inizio

472 (literal)

Pagina fine

479 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

34 (literal)

Rivista

European journal of nuclear medicine and molecular imaging (Rivista)

Note

ISI Web of Science (WOS) (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

1. School of Medicine, University of Milano-Bicocca, Milan, Italy 2. IBFM-CNR, Institute for Molecular Bioimaging and Physiology, Milan, Italy 3. Department of Diagnostic Radiology, H S. Gerardo Monza, Milan, Italy 4. Department of Nuclear Medicine, Scientific Institute San Raffaele, Milan, Italy 5. Department of Clinical Medicine Prevention and Biotechnology, Section of Medical Statistics, University of Milano-Bicocca, Milan, Italy 6. Department of Gynecology and Obstetrics, H S. Gerardo Monza, Milan, Italy 7. Department of Pathology, H S. Gerardo Monza, Milan, Italy 8. Department of Nuclear Medicine, H S. Gerardo Monza, Milan, Italy (literal)

Titolo

Post-therapy surveillance of patients with uterine cancers: value of integrated FDG PET/CT in the detection of recurrence. (literal)

Abstract

PURPOSE: The purpose of this study was to prospectively determine the diagnostic accuracy of PET/CT in the detection of recurrence in patients with treated uterine cancers. METHODS: Twenty-five women, ranging in age from 37 to 79 years (mean 58.9 years), who underwent primary surgical treatment for either a cervical or an endometrial cancer met the inclusion criterion of the study, which was suspicion of recurrence based on results of routine follow-up procedures. PET/CT was performed after administration of (18)F-fluorodeoxyglucose (FDG); two readers interpreted the images in consensus. Histopathological findings or correlation with results of subsequent clinical and imaging follow-up examinations served as the reference standard. Diagnostic accuracy of PET/CT was reported in terms of the proportion of correctly classified patients and lesion sites. RESULTS: Tumour recurrence was found at histopathological analysis or follow-up examinations after PET/CT in 14 (56%) of the 25 patients. Patient-based sensitivity, specificity, positive predictive value, negative predictive value and accuracy of PET/CT for detection of tumour recurrence were 92.9%, 100.0%, 100.0%, 91.7% and 96.0%, respectively. Lesion site-based sensitivity, specificity, positive predictive value, negative predictive value and accuracy of PET/CT were 94.7%, 99.5%, 94.7%, 99.5% and 99.0%, respectively. CONCLUSION: This preliminary study shows that PET/CT may be an accurate method for the evaluation of recurrence in patients who have been treated for uterine cancers and are undergoing follow-up. (literal)

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