Tail anchored proteins in plants (Abstract/Poster in atti di convegno)

Type
Label
  • Tail anchored proteins in plants (Abstract/Poster in atti di convegno) (literal)
Anno
  • 2009-01-01T00:00:00+01:00 (literal)
Alternative label
  • Pedrazzini E. (2009)
    Tail anchored proteins in plants
    in 20th International Conference for Arabidopsis Research (ICAR), Edinburgh, Scotland, UK
    (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
  • Pedrazzini E. (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#note
  • 30/06/2009 - 04/07/2009 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#descrizioneSinteticaDelProdotto
  • Abstract: Tail-anchored (TA) proteins are a class of polypeptides integrated into the membrane by a C-terminally located hydrophobic sequence. TA proteins lack an N-terminal signal peptide and reach their destination within the cell by post-translational mechanisms. They are present in each of the three domains of life, performing a variety of essential functions on the cytosolic face of cellular membranes and, in several cases, determining organelle identity. A number of TA proteins insert directly into the lipid bilayer without the help of molecular machineries, suggesting that they may be ancestral proteins able to recruit lipids, contributing to the formation of intracellular compartments during cell evolution. Here, a bioinformatic approach was used to produce a catalogue of putative TA proteins encoded by the Arabidopsis thaliana genome, and intracellular localization was predicted based on features of well characterized TA proteins. A recent strategy aimed at improving the accumulation of recombinant proteins expressed in transgenic plants is also described. Work supported by the projects EU FP6 ‘Pharma-Planta’ [LSH-2002-1.2.5-2] and MIUR PRIN 20073YHRLE. (literal)
Titolo
  • Tail anchored proteins in plants (literal)
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