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Descrizione settore di intervento
  • La strategia del Dipartimento è articolata per livelli di complessità crescente, procedendo da un’organizzazione per attività e progetti che fa convergere i risultati delle attività di ricerca e sviluppo in tre principali aree di intervento: • Salute • Sostenibilità • Tecnologie convergenti (literal)
  • HEALTH - The research activity of the Department of Molecular Design in the area of HEALTH puts emphasis on the development of new molecular systems (synthetic and natural) and new materials, using the multidisciplinary competences and the high level research efforts, also in the field of the development of enabling technologies, of some of the most authoritative chemical research units active in the area of bio-molecular sciences at the National Research Council. The scientific tools to reach these targets span from the application of enabling technologies, such as nanosciences (nanotechnologies and nanoprobes), Structural Biology, HTS techniques, cellular biology and molecular biology (tailored bacteria, modified proteins, in vitro and in vivo testing), to the use of innovative methodologies for the screening of the biotechnological potential of naturally occurring chemical compounds/enzymes/bioprocesses (Bioprospecting) using innovative synthetic, extraction and purification strategies such as those based on preparation of rational molecular repertoires with parallel and combinatorial chemistry techniques. An important instrument is the use of modern computational methods, which are largely exploited to rationalize and understand the structure-function relationships of biological systems at different complexity level. The development of predictive in silico models, accounting for the molecular mechanisms of specific and selective biological activity, will allow the researchers to select in silico the best class of compounds for a well defined biological response. This will save time and money to approach the discovery process of new molecules. SUSTAINABILITY - The enhancement of the economy of our country through the pursuing of sustainable chemistry is one of the strategic issues of the Department of Molecular Design which has tightly linked one of its seven strategic projects with the topics inspiring the European Technology Platform for Sustainable Chemistry recently launched by the European Community (http://www.suschem.org/). Themes dealing with sustainable chemistry and development are nevertheless common to the whole set of strategic programs of the Department spanning from solar photochemistry and non conventional photovoltaic systems, to the development of new polymeric materials from renewable resources, to the application of in silico predictive methods for catalyst design and optimization, to the new hybrid and composite materials which provide affordable solutions in the fields of food packaging, home environment, sustainable mobility and energy where many aspects of sustainability are directly translated into economical concepts and effectiveness. CONVERGING TECHNOLGIES - The DPM research activities share this vision and are in full agreement with this global trend and particularly with the EU aim to build up a knowledge-based European society, that means to move from an intensive resources exploitation industry to a sustainable and knowledge-based one. Nanoscience and nanotechnologies are well-recognized enabling tools for the fulfillment of this goal, and major breakthroughs are predicted for multidisciplinary converging technologies. The application of nanotechnologies to fabrication of goods and products with associated high degree of knowledge will transform radically the traditional industry and related production processes. NBIC convergence requires, and is made possible, by the radically new capabilities to understand and manipulate matter at molecular and atomic levels associated with nanoscience and nanotechnology. The contribution of DPM to CTs concerns the design, modelling and synthesis of innovative materials endowed with defined macroscopic functionalities based on specific and cooperative molecular properties as well as the integration of traditional materials with novel nano and molecular building blocks, through manipulation or nano-organization, improving quality and performances of present systems and obtaining unexpected properties. Among others, research fields at DPM concern optics, photonics and bio-photonics, sensing and bio-sensing, medical diagnostic and therapy, biocompatibility, energy saving and production, opto and microfluidic, data storage and information, development of advanced imaging and molecular manipulation techniques, envisioning the convergence of emerging nano and bio technologies. (literal)

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