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- Insights into the catalytic mechanism of the carbonic anhydrase family from the crystal structure of human isoform XIII (Contributo in atti di convegno) (Prodotto della ricerca)
- Insights into the carbonic anhydrase family: biochemical characterization of the human isozyme VII (Contributo in atti di convegno) (Prodotto della ricerca)
- Crystal structure of the catalytic domain of the tumor-associated hCA IX (Contributo in atti di convegno) (Prodotto della ricerca)
- Histone deacetylase and Cullin3-REN(KCTD11) ubiquitin ligase interplay regulates Hedgehog signalling through Gli acetylation. (Articolo in rivista) (Prodotto della ricerca)
- Drug design studies of the novel antitumor targets carbonic anhydrase IX and XII (Articolo in rivista) (Prodotto della ricerca)
- Multiple catalytically active thioredoxin folds: a winning strategy for many functions. (Articolo in rivista) (Prodotto della ricerca)
- Carbonic anhydrase inhibitors: crystallographic and solution binding studies for the interaction of a boron-containing aromatic sulfamide with mammalian isoforms I-XV. (Articolo in rivista) (Prodotto della ricerca)
- Anticancer steroid sulfatase inhibitors: Synthesis of a potent fluorinated second-generation agent, in vitro and in vivo activities, molecular modeling, and protein crystallography. (Articolo in rivista) (Prodotto della ricerca)
- STRUCTURAL AND FUNCTIONAL CHARACTERIZATION OF THE CUL3 ADAPTOR RENKCTD11 (Contributo in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1301)
- Functional And Structural Charateristics Of The Oxyanion Hole In A Thermophilic Esterase From Alyciclobacillus Acidocaldarius (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Carbonic anhydrase inhibitors: Inhibition of human, bacterial, and archaeal isozymes with benzene-1,3-disulfonamides - Solution and crystallographic studies (Articolo in rivista) (Prodotto della ricerca)
- Antiobesity carbonic anhydrase inhibitors (Articolo in rivista) (Prodotto della ricerca)
- Anticancer carbonic anhydrase inhibitors: a patent review (2008-2013) (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Kinetic and anion inhibition studies of a beta-carbonic anhydrase (FbiCA 1) from the C-4 plant Flaveria bidentis (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Carbonic Anhydrase inhibitors: bioreductive nitro-containing sulfonamides targeting the tumor-associated isoforms CA IX and XII (Abstract/Poster in atti di convegno) (Prodotto della ricerca)
- Carbonic anhydrase inhibitors: binding of indanesulfonamides to the human isoform II (Articolo in rivista) (Prodotto della ricerca)
- Investigations of the esterase, phosphatase, and sulfatase activities of the cytosolic mammalian carbonic anhydrase isoforms I, II, and XIII with 4-nitrophenyl esters as substrates (Articolo in rivista) (Prodotto della ricerca)
- Exploring the antioxidant system of Sulfolobus solfataricus: structural and functional analysis of peroxiredoxin Bcp1 (Abstract/Poster in atti di convegno) (Prodotto della ricerca)
- Are carbonic anhydrase inhibitors suitable for obtaining antiobesity drugs? (Articolo in rivista) (Prodotto della ricerca)
- The crystal structure of an EST2 mutant unveils structural insights on the H group of the carboxylesterase/lipase family. (Articolo in rivista) (Prodotto della ricerca)
- Functional and structural features of the oxyanion hole in a thermophilic esterase from Alicyclobacillus acidocaldarius (Articolo in rivista) (Prodotto della ricerca)
- Hydroxamate represents a versatile zinc binding group for the development of new carbonic anhydrase inhibitors (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Carbonic anhydrase inhibitors: bioreductive nitro-containing sulfonamides with selectivity for targeting the tumor associated isoforms IX and XII. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- A novel member of the protein disulfide oxidoreductase family from Aeropyrum pernix K1: structure, function and electrostatics. (Articolo in rivista) (Prodotto della ricerca)
- Carbonic Anhydrase Inhibitors: X-ray and Molecular Modeling Study for the Interaction of a Fluorescent Antitumor Sulfonamide with Isozyme II and IX (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Structure-activity relationships of C-17 cyano-substituted estratrienes as anticancer agents (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Crystal structure of an S-formylglutathione hydrolase from pseudoalteromonas haloplanktis TAC125. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Hydrophobic Substituents of the Phenylmethylsulfamide Moiety Can Be Used for the Development of New Selective Carbonic Anhydrase Inhibitors (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Crystallization and preliminary x-ray diffraction studies of Aes acetyl-esterase from Escherichia coli. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Metal ion substitution in the catalytic site greatly affects the binding of sulfhydryl-containing compounds to leucyl aminopeptidase (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Interactome analysis of carbonic anhydrase IX in normoxic and hypoxic conditions (Contributo in atti di convegno) (Prodotto della ricerca)
- ADVANCES IN THE INHIBITORY AND STRUCTURAL INVESTIGATIONS ON CARBONIC ANHYDRASE ISOZYMES XIII AND XV In Drug Design of Zinc-Enzyme Inhibitors: Functional, Structural, and Disease Applications (Contributo in volume (capitolo o saggio)) (Prodotto della ricerca)
- Structure and inhibition insights into Carbonic anhydrase CDCA1 from marine diatom Thalassiosira Weissflogii. (Contributo in atti di convegno) (Prodotto della ricerca)
- DRUG DESIGN OF ANTIOBESITY CARBONIC ANHYDRASE INHIBITORS. In Drug Design of Zinc-Enzyme Inhibitors: Functional, Structural, and Disease Applications (Contributo in volume (capitolo o saggio)) (Prodotto della ricerca)
- Carbonic anhydrase inhibitors: comparison of aliphatic sulfamate/bis-sulfamate adducts with isozimes II and IX (Contributo in atti di convegno) (Prodotto della ricerca)
- The crystal structure of CA I/Topiramate complex provides useful insights into rational drug design of anti-obesity drug (Contributo in atti di convegno) (Prodotto della ricerca)
- Structural and inhibition insights into carbonic anhydrase CDCA1 from the marine diatom Thalassiosira weissflogii (Articolo in rivista) (Prodotto della ricerca)
- Carbonic anhydrase inhibitors: stacking with Phe131 determines active site binding region of inhibitors as exemplified by the X-ray crystal structure of a membrane-impermeant antitumor sulfonamide complexed with isozyme II. (Articolo in rivista) (Prodotto della ricerca)
- Carbonic anhydrase inhibitors: binding of an antiglaucoma glycosyl-sulfanilamide derivative to human isoform II and its consequences for the drug design of enzyme inhibitors incorporating sugar moieties (Articolo in rivista) (Prodotto della ricerca)
- Carbonic anhydrase inhibitors: X-ray crystal structure of a benzenesulfonamide strong CA II and CA IX inhibitor bearing a pentafluorophenylaminothioureido tail in complex with isozyme II (Articolo in rivista) (Prodotto della ricerca)
- Recent Advances in Research on the Most Novel Carbonic Anhydrases, CA XIII and XV (Articolo in rivista) (Prodotto della ricerca)
- Carbonic anhydrase inhibitors. Zonisamide is an effective inhibitor of the cytosolic isozyme II and mitochondrial isozyme V: solution and X-ray crystallographic studies. (Articolo in rivista) (Prodotto della ricerca)
- Carbonic anhydrase inhibitors: the X-ray crystal structure of ethoxzolamide complexed to human isoform II reveals the importance of Thr200 and Gln92 for obtaining tight-binding inhibitors. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- 2-Substituted Estradiol Bis-sulfamates, Multitargeted Antitumor Agents: Synthesis, In Vitro SAR, Protein Crystallography, and In Vivo Activity (Articolo in rivista) (Prodotto della ricerca)
- Dithiocarbamates are strong inhibitors of the beta-class fungal carbonic anhydrases from Cryptococcus neoformans, Candidaalbicans and Candida glabrata (Articolo in rivista) (Prodotto della ricerca)
- Carbonic anhydrase inhibitors: hypoxia-activatable sulfonamides incorporating disulfide bonds that target the tumor-associated isoform IX (Articolo in rivista) (Prodotto della ricerca)
- A substrate-induced switch in the reaction mechanism of a thermophilic esterase. Kinetic evidences and structutal basis (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- STRUCTURAL CHARACTERIZATION OF HUMAN CARBONIC ANHYDRASE (Contributo in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1301)
- STRUCTURAL CHARACTERIZATION OF CARBONIC ANHYDRASE INHIBITORS INCORPORATING NEW METAL BINDING FUNCTIONALITIES (Contributo in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1301)
- Carbonic anhydrase inhibitors: Valdecoxib binds to a different active site region of the human isoform II as compared to the structurally related cyclooxygenase II \"selective\" inhibitor celecoxib. (Articolo in rivista) (Prodotto della ricerca)
- Carbonic anhydrase VII is S-glutathionylated without loss of catalytic activity and affinity for sulfonamide inhibitors (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- (In)organic anions as carbonic anhydrase inhibitors (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- CARBONIC ANHYDRASE INHIBITORS: HYPOXIA-ACTIVATABLE SULFONAMIDES INCORPORATING DISULFIDE BONDS THAT TARGET THE TUMOR-ASSOCIATED ISOFORM I (Contributo in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1301)
- Insights into the catalytic mechanism of the carbonic anhydrase family from the crystal structure of human isoform (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
- C68 from the Sulfolobus islandicus plasmid-virus pSSVx is a novelmember of the AbrB-like transcription factor family (Articolo in rivista) (Prodotto della ricerca)
- CARBONIC ANHYDRASE INHIBITORS: X-RAY CRYSTALLOGRAPHIC STUDIES FOR THE BINDING OF 5-AMINO-1,3,4-THIADIZOLE-2-SULFONAMIDE AND 5-(4-AMINO-3-CHLORO-5-FLUOROPHENYLSULFONAMIDO)-1,3,4-THIADIAZOLE-2-SULFONAMIDE TO HUMAN ISOFORM II (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Carbonic anhydraseinhibitors: X-ray crystallographic studies for the binding of N-substitutedbenzenesulfonamides to human isoform II (Articolo in rivista) (Prodotto della ricerca)
- Structural basis for the rational design of new anti-Brucella agents: The crystal structure of the C366S mutant of l-histidinol dehydrogenase from Brucella suis. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- HE CRYSTAL STRUCTURE OF A FERULOYL ESTERASE FROM THE PSYCHROPHILIC BACTERIUM PSEUDOALTEROMONAS HALOPLANKTIS TAC125 (Contributo in atti di convegno) (Prodotto della ricerca)
- Crystal structure of the catalytic domain of the tumor-associated human carbonic anhydrase IX. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Carbonic Anhydrase Inhibitors. Comparison of Aliphatic Sulfamate/Bis-sulfamate Adducts with Isozymes II and IX as a Platform for Designing Tight-Binding, More Isoform-Selective Inhibitors (Articolo in rivista) (Prodotto della ricerca)
- The crystal structure of the (Zn/Zn)bLAP/zofenoprilat complex. (Abstract/Comunicazione in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1106)
- STRUCTURAL AND FUNCTIONAL INSIGHTS INTO BCP4: COMPONENT OF THE ANTIOXIDANT SYSTEM OF SULFOLOBUS SOLFATARICUS (Contributo in atti di convegno) (Prodotto della ricerca)
- DEVELOPMENTS IN THE DESIGN OF ANTITUMOR CARBONIC ANHYDRASE INHIBITORS (Contributo in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1301)
- CRYSTAL STRUCTURE OF A PROTEIN DISULFIDE OXIDOREDUCTASE FROM AEROPYRUM PERNIX K1 (Contributo in atti di convegno) (Prodotto della ricerca)
- THE CRYSTAL STRUCTURE OF HCA I/TOPIRAMATE COMPLEX PROVIDES USEFUL INSIGHTS INTO RATIONAL DRUG DESIGN OF ANTI-OBESITY DRUGS (Contributo in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1301)
- Sulfolobus solfataricus thiol redox puzzle: Characterization of an atypical protein disulfide oxidoreductase (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Insights into peptide nucleic acid (PNA) structural features: The crystal structure of a D-lysine-based chiral PNA-DNA duplex (Articolo in rivista) (Prodotto della ricerca)
- An integrated structural and computational study of the thermostability of two thioredoxin mutants from Alicyclobacillus acidocaldarius (Articolo in rivista) (Prodotto della ricerca)
- Crystallization and preliminary X-ray diffraction studies of a protein disulfide oxidoreductase from Aquifex aeolicus. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Carbonic anhydrase inhibitors as emerging drugs for the treatment of obesity (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- The crystal structure of a hyper-thermophilic carboxylesterase from the Archaeon Archaeoglobus fulgidus (Articolo in rivista) (Prodotto della ricerca)
- Biochemical and Structural Analysis of a New Carbonic Anhydrase from the Thermophilic Bacterium Sulfurihydrogenibium sp. YO3AOP1 (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
- Molecular modeling study for the binding of zonisamide and topiramate to the human mitochondrial carbonic anhydrase isoform VA (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Structural characterization of human carbonic anhydrase VII. (Contributo in atti di convegno) (Prodotto della ricerca)
- Initial structural characterization of Brucella suis hystidinol dehydrogenase. (Contributo in atti di convegno) (Prodotto della ricerca)
- Structural insights into Carbonic anhydrase CDCA1 from marine diatom Thalassiosira Weissflogii (Contributo in atti di convegno) (Prodotto della ricerca)
- Insights into plant beta- carbonic anhydrase isolated from Flaveria Bidentis (Contributo in atti di convegno) (Prodotto della ricerca)
- Human Carbonic Anhydrase VII protects cells from oxidative damage (Contributo in atti di convegno) (Prodotto della ricerca)
- Which carbonic anhydrases are targeted by the antiepileptic sulfonamides and sulfamates? (Articolo in rivista) (Prodotto della ricerca)
- Insights into Carbonic Anhydrase VII functional role (Contributo in atti di convegno) (Prodotto della ricerca)
- A CUL3-DERIVED PEPTIDE BINDING DIFFERENT MEMBERS OF THE KCTD FAMILY (Contributo in atti di convegno) (Prodotto della ricerca)
- PRELIMINARY CHARACTERIZATION OF BRUCELLA SUIS HYSTIDINOL DEHYDROGENASE (Contributo in atti di convegno) (Prodotto della ricerca)
- Biochemical and Structural Analysis of a New Carbonic Anhydrase from the Thermophilic Bacterium Sulfurihydrogenibium sp. YO3AOP1 (Contributo in atti di convegno) (Prodotto della ricerca)
- Insights into the catalytic mechanism of the Bcp family: Functional and structural analysis of Bcp1 from Sulfolobus solfataricus (Articolo in rivista) (Prodotto della ricerca)
- Carbonic Anhydrase IX as a Target for Designing Novel Anticancer Drugs. (Articolo in rivista) (Prodotto della ricerca)
- Carbonic anhydrase IX: Biochemical and crystallographic characterization of a novel antitumor target. (Articolo in rivista) (Prodotto della ricerca)
- Recent advances in structural studies of the carbonic anhydrase family: the crystal structure of human CA IX and CA XIII. (Articolo in rivista) (Prodotto della ricerca)
- -RAY CRYSTALLOGRAPHY OF CARBONIC ANHYDRASE INHIBITORS AND ITS IMPORTANCE IN DRUG DESIGN. In Drug Design of Zinc-Enzyme Inhibitors: Functional, Structural, and Disease Applications (Contributo in volume (capitolo o saggio)) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1201)
- Crystal structure of human carbonic anhydrase XIII and its complex with the inhibitor acetazolamide (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Metal ion substitution in catalytic site greatly affects the binding of sulfhydryl-containing compounds to bovine leucyl aminopeptidase (Articolo in rivista) (Prodotto della ricerca)
- Design of Weakly Basic Thrombin Inhibitors Incorporating Novel P1 Binding Functions: Molecular and X-ray Crystallographic Studies. (Articolo in rivista) (Prodotto della ricerca)
- Multiple binding modes of inhibitors to carbonic anhydrases: How to design specific drugs targeting 15 different isoforms? (Articolo in rivista) (Prodotto della ricerca)
- STRUCTURAL ANALYSIS OF THE TRANSCRIPTIONAL REGULATOR BALD16 FROM SULFOLOBUS SOLFATARICUS (Contributo in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1301)
- Biochemical characterization of CA IX, one of the most active Carbonic Anhydrase isozymes. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- CARBONIC ANHYDRASE INHIBITORS: X-RAY AND MOLECULAR MODELING STUDY FOR THE INTERACTION OF A FLUORESCENT ANTITUMOR SULFONAMIDE WITH ISOZYME II AND IX (Contributo in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1301)
- The first example of a significant active site conformational rearrangement in a carbonic anhydrase-inhibitor adduct: the carbonic anhydrase I-topiramate complex. (Articolo in rivista) (Prodotto della ricerca)
- X-ray structure of the first 'extremo-alfa-carbonic anhydrase', a dimeric enzyme from the thermophilic bacterium Sulfurihydrogenibium yellowstonense YO3AOP1 (Articolo in rivista) (Prodotto della ricerca)
- Exploring the catalytic mechanism of the first dimeric Bcp: Functional, structural and docking analyses of Bcp4 from Sulfolobus solfataricus. (Articolo in rivista) (Prodotto della ricerca)
- Structural analysis of BldR from Sulfolobus solfataricus provides insights into the molecular basis of transcriptional activation in Archaea by MarR family proteins (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Insights Into The Catalytic Mechanism Of The Bcp Family: Functional And Structural Analysis Of Bcp1 From Sulfolobus Sulfataricus (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
- Identification and characterization of a new form of oncosuppressor KCTD11 (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
- Characterization of Carbonic Anhydrase IX Interactome Reveals Proteins Assisting Its Nuclear Localization in Hypoxic Cells (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- The proteoglycan region of the tumor-associated carbonic anhydrase isoform IX acts as anintrinsic buffer optimizing CO2 hydration at acidic pH values characteristic of solid tumors (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Carbonic anhydrase inhibitors. Comparison of aliphatic sulfamate/bis-sulfamate adducts with isozymes II and IX as a platform for designing tight-binding, more isoform-selective inhibitors (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- New insights in PNA structural features: the crystal structure of a D-Lysine-based chiral PNA-DNA duplex (Comunicazione a convegno) (Prodotto della ricerca)
- Italy ? Japan Symposium (Comunicazione a convegno) (Prodotto della ricerca)
- Crystallization and preliminary x-ray diffraction studies of a protein disulfide oxidoreductase from Aeropyrum pernix K1 (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- FAOX enzymes from Aspergillus sp as enzymatic tools for preventing AGE formation . In: 11th Maillard Reaction (Contributo in atti di convegno) (Prodotto della ricerca)
- Insights into Carbonic anhydrase IX interactome in normoxic and hypoxic conditions (Contributo in atti di convegno) (Prodotto della ricerca)
- Crystal structure of the C183S/C217S mutant of human CA VII in complex with acetazolamide. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Inhibition of the R1 fragment of the cadmium-containing zeta-class carbonic anhydrase from the diatom Thalassiosira weissflogii with anions. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
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- Autore CNR
- STRUCTURAL ANALYSIS OF THE TRANSCRIPTIONAL REGULATOR BALD16 FROM SULFOLOBUS SOLFATARICUS (Contributo in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1301)
- CARBONIC ANHYDRASE INHIBITORS: X-RAY AND MOLECULAR MODELING STUDY FOR THE INTERACTION OF A FLUORESCENT ANTITUMOR SULFONAMIDE WITH ISOZYME II AND IX (Contributo in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1301)
- A CUL3-DERIVED PEPTIDE BINDING DIFFERENT MEMBERS OF THE KCTD FAMILY (Contributo in atti di convegno) (Prodotto della ricerca)
- PRELIMINARY CHARACTERIZATION OF BRUCELLA SUIS HYSTIDINOL DEHYDROGENASE (Contributo in atti di convegno) (Prodotto della ricerca)
- CARBONIC ANHYDRASE INHIBITORS: HYPOXIA-ACTIVATABLE SULFONAMIDES INCORPORATING DISULFIDE BONDS THAT TARGET THE TUMOR-ASSOCIATED ISOFORM I (Contributo in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1301)
- THE CRYSTAL STRUCTURE OF HCA I/TOPIRAMATE COMPLEX PROVIDES USEFUL INSIGHTS INTO RATIONAL DRUG DESIGN OF ANTI-OBESITY DRUGS (Contributo in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1301)
- STRUCTURAL AND FUNCTIONAL INSIGHTS INTO BCP4: COMPONENT OF THE ANTIOXIDANT SYSTEM OF SULFOLOBUS SOLFATARICUS (Contributo in atti di convegno) (Prodotto della ricerca)
- STRUCTURAL AND FUNCTIONAL CHARACTERIZATION OF THE CUL3 ADAPTOR RENKCTD11 (Contributo in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1301)
- The crystal structure of an EST2 mutant unveils structural insights on the H group of the carboxylesterase/lipase family. (Articolo in rivista) (Prodotto della ricerca)
- Carbonic anhydrase inhibitors. Zonisamide is an effective inhibitor of the cytosolic isozyme II and mitochondrial isozyme V: solution and X-ray crystallographic studies. (Articolo in rivista) (Prodotto della ricerca)
- Carbonic anhydrase inhibitors: X-ray crystal structure of a benzenesulfonamide strong CA II and CA IX inhibitor bearing a pentafluorophenylaminothioureido tail in complex with isozyme II (Articolo in rivista) (Prodotto della ricerca)
- Carbonic anhydrase inhibitors: hypoxia-activatable sulfonamides incorporating disulfide bonds that target the tumor-associated isoform IX (Articolo in rivista) (Prodotto della ricerca)
- 2-Substituted Estradiol Bis-sulfamates, Multitargeted Antitumor Agents: Synthesis, In Vitro SAR, Protein Crystallography, and In Vivo Activity (Articolo in rivista) (Prodotto della ricerca)
- Structure-activity relationships of C-17 cyano-substituted estratrienes as anticancer agents (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Insights into the catalytic mechanism of the Bcp family: Functional and structural analysis of Bcp1 from Sulfolobus solfataricus (Articolo in rivista) (Prodotto della ricerca)
- Which carbonic anhydrases are targeted by the antiepileptic sulfonamides and sulfamates? (Articolo in rivista) (Prodotto della ricerca)
- Recent advances in structural studies of the carbonic anhydrase family: the crystal structure of human CA IX and CA XIII. (Articolo in rivista) (Prodotto della ricerca)
- Carbonic anhydrase IX: Biochemical and crystallographic characterization of a novel antitumor target. (Articolo in rivista) (Prodotto della ricerca)
- Carbonic Anhydrase Inhibitors: X-ray and Molecular Modeling Study for the Interaction of a Fluorescent Antitumor Sulfonamide with Isozyme II and IX (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Carbonic anhydrase inhibitors: Inhibition of human, bacterial, and archaeal isozymes with benzene-1,3-disulfonamides - Solution and crystallographic studies (Articolo in rivista) (Prodotto della ricerca)
- Antiobesity carbonic anhydrase inhibitors (Articolo in rivista) (Prodotto della ricerca)
- Functional And Structural Charateristics Of The Oxyanion Hole In A Thermophilic Esterase From Alyciclobacillus Acidocaldarius (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Anticancer steroid sulfatase inhibitors: Synthesis of a potent fluorinated second-generation agent, in vitro and in vivo activities, molecular modeling, and protein crystallography. (Articolo in rivista) (Prodotto della ricerca)
- Investigations of the esterase, phosphatase, and sulfatase activities of the cytosolic mammalian carbonic anhydrase isoforms I, II, and XIII with 4-nitrophenyl esters as substrates (Articolo in rivista) (Prodotto della ricerca)
- Are carbonic anhydrase inhibitors suitable for obtaining antiobesity drugs? (Articolo in rivista) (Prodotto della ricerca)
- Carbonic anhydrase inhibitors: binding of indanesulfonamides to the human isoform II (Articolo in rivista) (Prodotto della ricerca)
- Crystal structure of the C183S/C217S mutant of human CA VII in complex with acetazolamide. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Inhibition of the R1 fragment of the cadmium-containing zeta-class carbonic anhydrase from the diatom Thalassiosira weissflogii with anions. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Multiple catalytically active thioredoxin folds: a winning strategy for many functions. (Articolo in rivista) (Prodotto della ricerca)
- Carbonic anhydrase inhibitors: crystallographic and solution binding studies for the interaction of a boron-containing aromatic sulfamide with mammalian isoforms I-XV. (Articolo in rivista) (Prodotto della ricerca)
- Histone deacetylase and Cullin3-REN(KCTD11) ubiquitin ligase interplay regulates Hedgehog signalling through Gli acetylation. (Articolo in rivista) (Prodotto della ricerca)
- Drug design studies of the novel antitumor targets carbonic anhydrase IX and XII (Articolo in rivista) (Prodotto della ricerca)
- Crystallization and preliminary X-ray diffraction studies of a protein disulfide oxidoreductase from Aquifex aeolicus. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- An integrated structural and computational study of the thermostability of two thioredoxin mutants from Alicyclobacillus acidocaldarius (Articolo in rivista) (Prodotto della ricerca)
- Insights into peptide nucleic acid (PNA) structural features: The crystal structure of a D-lysine-based chiral PNA-DNA duplex (Articolo in rivista) (Prodotto della ricerca)
- Carbonic anhydrase inhibitors: Valdecoxib binds to a different active site region of the human isoform II as compared to the structurally related cyclooxygenase II \"selective\" inhibitor celecoxib. (Articolo in rivista) (Prodotto della ricerca)
- CARBONIC ANHYDRASE INHIBITORS: X-RAY CRYSTALLOGRAPHIC STUDIES FOR THE BINDING OF 5-AMINO-1,3,4-THIADIZOLE-2-SULFONAMIDE AND 5-(4-AMINO-3-CHLORO-5-FLUOROPHENYLSULFONAMIDO)-1,3,4-THIADIAZOLE-2-SULFONAMIDE TO HUMAN ISOFORM II (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Carbonic anhydrase inhibitors: binding of an antiglaucoma glycosyl-sulfanilamide derivative to human isoform II and its consequences for the drug design of enzyme inhibitors incorporating sugar moieties (Articolo in rivista) (Prodotto della ricerca)
- Carbonic anhydrase inhibitors: the X-ray crystal structure of ethoxzolamide complexed to human isoform II reveals the importance of Thr200 and Gln92 for obtaining tight-binding inhibitors. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Recent Advances in Research on the Most Novel Carbonic Anhydrases, CA XIII and XV (Articolo in rivista) (Prodotto della ricerca)
- The proteoglycan region of the tumor-associated carbonic anhydrase isoform IX acts as anintrinsic buffer optimizing CO2 hydration at acidic pH values characteristic of solid tumors (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Carbonic anhydrase inhibitors. Comparison of aliphatic sulfamate/bis-sulfamate adducts with isozymes II and IX as a platform for designing tight-binding, more isoform-selective inhibitors (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Exploring the catalytic mechanism of the first dimeric Bcp: Functional, structural and docking analyses of Bcp4 from Sulfolobus solfataricus. (Articolo in rivista) (Prodotto della ricerca)
- The first example of a significant active site conformational rearrangement in a carbonic anhydrase-inhibitor adduct: the carbonic anhydrase I-topiramate complex. (Articolo in rivista) (Prodotto della ricerca)
- Carbonic anhydrase inhibitors as emerging drugs for the treatment of obesity (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Metal ion substitution in catalytic site greatly affects the binding of sulfhydryl-containing compounds to bovine leucyl aminopeptidase (Articolo in rivista) (Prodotto della ricerca)
- HE CRYSTAL STRUCTURE OF A FERULOYL ESTERASE FROM THE PSYCHROPHILIC BACTERIUM PSEUDOALTEROMONAS HALOPLANKTIS TAC125 (Contributo in atti di convegno) (Prodotto della ricerca)
- CRYSTAL STRUCTURE OF A PROTEIN DISULFIDE OXIDOREDUCTASE FROM AEROPYRUM PERNIX K1 (Contributo in atti di convegno) (Prodotto della ricerca)
- DEVELOPMENTS IN THE DESIGN OF ANTITUMOR CARBONIC ANHYDRASE INHIBITORS (Contributo in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1301)
- STRUCTURAL CHARACTERIZATION OF HUMAN CARBONIC ANHYDRASE (Contributo in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1301)
- STRUCTURAL CHARACTERIZATION OF CARBONIC ANHYDRASE INHIBITORS INCORPORATING NEW METAL BINDING FUNCTIONALITIES (Contributo in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1301)
- Insights into the catalytic mechanism of the carbonic anhydrase family from the crystal structure of human isoform (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
- Exploring the antioxidant system of Sulfolobus solfataricus: structural and functional analysis of peroxiredoxin Bcp1 (Abstract/Poster in atti di convegno) (Prodotto della ricerca)
- Carbonic Anhydrase inhibitors: bioreductive nitro-containing sulfonamides targeting the tumor-associated isoforms CA IX and XII (Abstract/Poster in atti di convegno) (Prodotto della ricerca)
- ADVANCES IN THE INHIBITORY AND STRUCTURAL INVESTIGATIONS ON CARBONIC ANHYDRASE ISOZYMES XIII AND XV In Drug Design of Zinc-Enzyme Inhibitors: Functional, Structural, and Disease Applications (Contributo in volume (capitolo o saggio)) (Prodotto della ricerca)
- DRUG DESIGN OF ANTIOBESITY CARBONIC ANHYDRASE INHIBITORS. In Drug Design of Zinc-Enzyme Inhibitors: Functional, Structural, and Disease Applications (Contributo in volume (capitolo o saggio)) (Prodotto della ricerca)
- New insights in PNA structural features: the crystal structure of a D-Lysine-based chiral PNA-DNA duplex (Comunicazione a convegno) (Prodotto della ricerca)
- Italy ? Japan Symposium (Comunicazione a convegno) (Prodotto della ricerca)
- Insights Into The Catalytic Mechanism Of The Bcp Family: Functional And Structural Analysis Of Bcp1 From Sulfolobus Sulfataricus (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
- -RAY CRYSTALLOGRAPHY OF CARBONIC ANHYDRASE INHIBITORS AND ITS IMPORTANCE IN DRUG DESIGN. In Drug Design of Zinc-Enzyme Inhibitors: Functional, Structural, and Disease Applications (Contributo in volume (capitolo o saggio)) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1201)
- A substrate-induced switch in the reaction mechanism of a thermophilic esterase. Kinetic evidences and structutal basis (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Crystallization and preliminary x-ray diffraction studies of a protein disulfide oxidoreductase from Aeropyrum pernix K1 (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Structural analysis of BldR from Sulfolobus solfataricus provides insights into the molecular basis of transcriptional activation in Archaea by MarR family proteins (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Crystal structure of human carbonic anhydrase XIII and its complex with the inhibitor acetazolamide (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Biochemical characterization of CA IX, one of the most active Carbonic Anhydrase isozymes. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Design of Weakly Basic Thrombin Inhibitors Incorporating Novel P1 Binding Functions: Molecular and X-ray Crystallographic Studies. (Articolo in rivista) (Prodotto della ricerca)
- Functional and structural features of the oxyanion hole in a thermophilic esterase from Alicyclobacillus acidocaldarius (Articolo in rivista) (Prodotto della ricerca)
- A novel member of the protein disulfide oxidoreductase family from Aeropyrum pernix K1: structure, function and electrostatics. (Articolo in rivista) (Prodotto della ricerca)
- Molecular modeling study for the binding of zonisamide and topiramate to the human mitochondrial carbonic anhydrase isoform VA (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- The crystal structure of a hyper-thermophilic carboxylesterase from the Archaeon Archaeoglobus fulgidus (Articolo in rivista) (Prodotto della ricerca)
- Crystal structure of the catalytic domain of the tumor-associated human carbonic anhydrase IX. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Structural and inhibition insights into carbonic anhydrase CDCA1 from the marine diatom Thalassiosira weissflogii (Articolo in rivista) (Prodotto della ricerca)
- Metal ion substitution in the catalytic site greatly affects the binding of sulfhydryl-containing compounds to leucyl aminopeptidase (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Crystallization and preliminary x-ray diffraction studies of Aes acetyl-esterase from Escherichia coli. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Crystal structure of an S-formylglutathione hydrolase from pseudoalteromonas haloplanktis TAC125. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Identification and characterization of a new form of oncosuppressor KCTD11 (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
- Carbonic anhydrase inhibitors: bioreductive nitro-containing sulfonamides with selectivity for targeting the tumor associated isoforms IX and XII. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Carbonic anhydrase VII is S-glutathionylated without loss of catalytic activity and affinity for sulfonamide inhibitors (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Carbonic anhydrase inhibitors: stacking with Phe131 determines active site binding region of inhibitors as exemplified by the X-ray crystal structure of a membrane-impermeant antitumor sulfonamide complexed with isozyme II. (Articolo in rivista) (Prodotto della ricerca)
- Carbonic Anhydrase Inhibitors. Comparison of Aliphatic Sulfamate/Bis-sulfamate Adducts with Isozymes II and IX as a Platform for Designing Tight-Binding, More Isoform-Selective Inhibitors (Articolo in rivista) (Prodotto della ricerca)
- (In)organic anions as carbonic anhydrase inhibitors (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Carbonic anhydraseinhibitors: X-ray crystallographic studies for the binding of N-substitutedbenzenesulfonamides to human isoform II (Articolo in rivista) (Prodotto della ricerca)
- Dithiocarbamates are strong inhibitors of the beta-class fungal carbonic anhydrases from Cryptococcus neoformans, Candidaalbicans and Candida glabrata (Articolo in rivista) (Prodotto della ricerca)
- Carbonic Anhydrase IX as a Target for Designing Novel Anticancer Drugs. (Articolo in rivista) (Prodotto della ricerca)
- Interactome analysis of carbonic anhydrase IX in normoxic and hypoxic conditions (Contributo in atti di convegno) (Prodotto della ricerca)
- Structure and inhibition insights into Carbonic anhydrase CDCA1 from marine diatom Thalassiosira Weissflogii. (Contributo in atti di convegno) (Prodotto della ricerca)
- The crystal structure of CA I/Topiramate complex provides useful insights into rational drug design of anti-obesity drug (Contributo in atti di convegno) (Prodotto della ricerca)
- Carbonic anhydrase inhibitors: comparison of aliphatic sulfamate/bis-sulfamate adducts with isozimes II and IX (Contributo in atti di convegno) (Prodotto della ricerca)
- Structural basis for the rational design of new anti-Brucella agents: The crystal structure of the C366S mutant of l-histidinol dehydrogenase from Brucella suis. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- C68 from the Sulfolobus islandicus plasmid-virus pSSVx is a novelmember of the AbrB-like transcription factor family (Articolo in rivista) (Prodotto della ricerca)
- Anticancer carbonic anhydrase inhibitors: a patent review (2008-2013) (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Kinetic and anion inhibition studies of a beta-carbonic anhydrase (FbiCA 1) from the C-4 plant Flaveria bidentis (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Characterization of Carbonic Anhydrase IX Interactome Reveals Proteins Assisting Its Nuclear Localization in Hypoxic Cells (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- FAOX enzymes from Aspergillus sp as enzymatic tools for preventing AGE formation . In: 11th Maillard Reaction (Contributo in atti di convegno) (Prodotto della ricerca)
- Insights into Carbonic anhydrase IX interactome in normoxic and hypoxic conditions (Contributo in atti di convegno) (Prodotto della ricerca)
- Crystal structure of the catalytic domain of the tumor-associated hCA IX (Contributo in atti di convegno) (Prodotto della ricerca)
- Insights into the carbonic anhydrase family: biochemical characterization of the human isozyme VII (Contributo in atti di convegno) (Prodotto della ricerca)
- Insights into the catalytic mechanism of the carbonic anhydrase family from the crystal structure of human isoform XIII (Contributo in atti di convegno) (Prodotto della ricerca)
- X-ray structure of the first 'extremo-alfa-carbonic anhydrase', a dimeric enzyme from the thermophilic bacterium Sulfurihydrogenibium yellowstonense YO3AOP1 (Articolo in rivista) (Prodotto della ricerca)
- Biochemical and Structural Analysis of a New Carbonic Anhydrase from the Thermophilic Bacterium Sulfurihydrogenibium sp. YO3AOP1 (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
- Biochemical and Structural Analysis of a New Carbonic Anhydrase from the Thermophilic Bacterium Sulfurihydrogenibium sp. YO3AOP1 (Contributo in atti di convegno) (Prodotto della ricerca)
- Human Carbonic Anhydrase VII protects cells from oxidative damage (Contributo in atti di convegno) (Prodotto della ricerca)
- Insights into Carbonic Anhydrase VII functional role (Contributo in atti di convegno) (Prodotto della ricerca)
- Insights into plant beta- carbonic anhydrase isolated from Flaveria Bidentis (Contributo in atti di convegno) (Prodotto della ricerca)
- Structural insights into Carbonic anhydrase CDCA1 from marine diatom Thalassiosira Weissflogii (Contributo in atti di convegno) (Prodotto della ricerca)
- Initial structural characterization of Brucella suis hystidinol dehydrogenase. (Contributo in atti di convegno) (Prodotto della ricerca)
- Structural characterization of human carbonic anhydrase VII. (Contributo in atti di convegno) (Prodotto della ricerca)
- Hydrophobic Substituents of the Phenylmethylsulfamide Moiety Can Be Used for the Development of New Selective Carbonic Anhydrase Inhibitors (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- The crystal structure of the (Zn/Zn)bLAP/zofenoprilat complex. (Abstract/Comunicazione in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1106)
- Sulfolobus solfataricus thiol redox puzzle: Characterization of an atypical protein disulfide oxidoreductase (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Multiple binding modes of inhibitors to carbonic anhydrases: How to design specific drugs targeting 15 different isoforms? (Articolo in rivista) (Prodotto della ricerca)
- Hydroxamate represents a versatile zinc binding group for the development of new carbonic anhydrase inhibitors (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
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