Design and production of a chimeric resilin-, elastin-, and collagen-like engineered polypeptide (Articolo in rivista)

Type

• Prodotto della ricerca (Classe)
• Articolo in rivista (Classe)

Label

• Design and production of a chimeric resilin-, elastin-, and collagen-like engineered polypeptide (Articolo in rivista) (literal)

Anno

• 2011-01-01T00:00:00+01:00 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi

• 10.1021/bm2005388 (literal)

Alternative label

• Angelo Bracalello; Valentina Santopietro; Massimo Vassalli; Giovanni Marletta; Rosanna Del Gaudio; Brigida Bochicchio; Antonietta Pepe (2011)
  Design and production of a chimeric resilin-, elastin-, and collagen-like engineered polypeptide
  in Biomacromolecules
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• Angelo Bracalello; Valentina Santopietro; Massimo Vassalli; Giovanni Marletta; Rosanna Del Gaudio; Brigida Bochicchio; Antonietta Pepe (literal)

Pagina inizio

• 2957 (literal)

Pagina fine

• 2965 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 12 (literal)

Rivista

• Biomacromolecules (Rivista)

Note

• ISI Web of Science (WOS) (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• Department of Chemistry \"Antonio M. Tamburrro\", University of Basilicata, 85100 Potenza, Italy Institute of Biophysics of The National Research Council of Italy, 16149 Genova, Italy Department of Chemical Sciences, University of Catania, 95125 Catania, Italy Department of Biological Sciences, University of Naples \"Federico II\", 80134 Naples, Italy (literal)

Titolo

• Design and production of a chimeric resilin-, elastin-, and collagen-like engineered polypeptide (literal)

Abstract

• Protein-inspired biomaterials have gained great interest as an alternative to synthetic polymers, in particular, for their potential use as biomedical devices. The potential inspiring models are mainly proteins able to confer mechanical properties to tissues and organs, such as elasticity (elastin, resilin, spider silk) and strength (collagen, silk). The proper combination of repetitive sequences, each of them derived from different proteins, represents a useful tool for obtaining biomaterials with tailored mechanical properties and biological functions. In this report we describe the design, the production, and the preliminary characterization of a chimeric polypeptide, based on sequences derived from the highly resilient proteins resilin and elastin and from collagen-like sequences. The results show that the obtained chimeric recombinant material exhibits promising self-assembling properties. Young's modulus of the fibers was determined by AFM image analysis and lies in the range of 0.1-3 MPa in agreement with the expectations for elastin-like and resilin-like materials (literal)

Prodotto di

• Processi di membrana nella comunicazione intra- ed inter-cellulare (MD.P01.001.001) (Modulo)
• Istituto di biofisica (IBF) (Istituto)

Autore CNR

• MASSIMO VASSALLI (Unità di personale interno)

Incoming links:

Prodotto

• Istituto di biofisica (IBF) (Istituto)
• Processi di membrana nella comunicazione intra- ed inter-cellulare (MD.P01.001.001) (Modulo)

Autore CNR di

• MASSIMO VASSALLI (Unità di personale interno)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• Biomacromolecules (Rivista)