Minimal art: Or why small viral K(+) channels are good tools for understanding basic structure and function relations (Articolo in rivista)

Type
Label
  • Minimal art: Or why small viral K(+) channels are good tools for understanding basic structure and function relations (Articolo in rivista) (literal)
Anno
  • 2011-01-01T00:00:00+01:00 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi
  • 10.1016/j.bbamem.2010.04.008 (literal)
Alternative label
  • Thiel G, Baumeister D, Schroeder I, Kast SM, Van Etten JL, Moroni A (2011)
    Minimal art: Or why small viral K(+) channels are good tools for understanding basic structure and function relations
    in Biochimica et biophysica acta. Biomembranes
    (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
  • Thiel G, Baumeister D, Schroeder I, Kast SM, Van Etten JL, Moroni A (literal)
Pagina inizio
  • 580 (literal)
Pagina fine
  • 588 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume
  • 1808 (literal)
Rivista
Note
  • ISI Web of Science (WOS) (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
  • Tech Univ Darmstadt, Inst Bot, D-64287 Darmstadt, Germany [ 2 ] Tech Univ Dortmund, D-44227 Dortmund, Germany [ 3 ] Univ Nebraska, Dept Plant Pathol, Lincoln, NE 68583 USA [ 4 ] Univ Nebraska, Nebraska Ctr Virol, Lincoln, NE 68583 USA [ 5 ] Univ Milan, Dept Biol, I-20133 Milan, Italy [ 6 ] Univ Milan, CNR, Ist Biofis, I-20133 Milan, Italy (literal)
Titolo
  • Minimal art: Or why small viral K(+) channels are good tools for understanding basic structure and function relations (literal)
Abstract
  • Some algal viruses contain genes that encode proteins with the hallmarks of K(+) channels. One feature of these proteins is that they are less than 100 amino acids in size, which make them truly minimal for a K(+) channel protein. That is, they consist of only the pore module present in more complex K(+) channels. The combination of miniature size and the functional robustness of the viral K(+) channels make them ideal model systems for studying how K(+) channels work. Here we summarize recent structure/function correlates from these channels, which provide insight into functional properties such as gating, pharmacology and sorting in cells. (literal)
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