Cis-trans photolsomerization of the chromophore in the green fluorescent protein variant E(2)GFP: A molecular dynamics study (Articolo in rivista)

Type
Label
  • Cis-trans photolsomerization of the chromophore in the green fluorescent protein variant E(2)GFP: A molecular dynamics study (Articolo in rivista) (literal)
Anno
  • 2006-01-01T00:00:00+01:00 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi
  • 10.1016/j.chemphys.2005.09.032 (literal)
Alternative label
  • Nifosi, R; Tozzini, V (2006)
    Cis-trans photolsomerization of the chromophore in the green fluorescent protein variant E(2)GFP: A molecular dynamics study
    in Chemical physics (Print)
    (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
  • Nifosi, R; Tozzini, V (literal)
Pagina inizio
  • 358 (literal)
Pagina fine
  • 368 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume
  • 323 (literal)
Rivista
Note
  • ISI Web of Science (WOS) (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
  • Scuola Normale Super Pisa, CNR, INFM, NEST, I-56126 Pisa, Italy (literal)
Titolo
  • Cis-trans photolsomerization of the chromophore in the green fluorescent protein variant E(2)GFP: A molecular dynamics study (literal)
Abstract
  • By force-field molecular dynamics simulations we investigate the dynamics of cis-trans photoisomerization of the chromophore in the GFP mutant E(2)GFP (F64L/S65T/T203Y), and the rearrangements that allow the protein structure to accommodate the trans form of the chromophore. We find that in this new configuration the chromophore is less well coordinated with the Surrounding protein matrix. From this configuration the simulated trans-cis photoisomerization of the chromophore and the associated non-radiative decay are faster than in the cis-trans case. (c) 2005 Elsevier B.V. All rights reserved. (literal)
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