http://www.cnr.it/ontology/cnr/individuo/prodotto/ID971

Electrophoretic separation of nanoparticles with a discrete number of functional groups (Articolo in rivista)

Type

Label

Electrophoretic separation of nanoparticles with a discrete number of functional groups (Articolo in rivista) (literal)

Anno

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi

Alternative label

Sperling, RA; Pellegrino, T; Li, JK; Chang, WH; Parak, WJ (2006)
Electrophoretic separation of nanoparticles with a discrete number of functional groups
in Advanced functional materials (Print)
(literal)

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Pagina inizio

Pagina fine

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Rivista

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Note

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Univ Munich, Ctr Nanosci, D-80799 Munich, Germany; Chung Yuan Christian Univ, Ctr Nano Bioengn, Chungli 32023, Taiwan; Chung Yuan Christian Univ, R&D Ctr Membrane Technol, Chungli 32023, Taiwan; INFM, NNL, I-73100 Lecce, Italy (literal)

Titolo

Electrophoretic separation of nanoparticles with a discrete number of functional groups (literal)

Abstract

A concept is describe that facilitates the modification of colloidal nanoparticles of different materials with an exactly known number of variable functional groups. In particular, a procedure for the surface functionalization of nanoparticles with a controlled number of mono- or bifunctional poly(ethylene glycol) (PEG) molecules of suitable chain length is reported. Conjugates of nanoparticles with one, two, and three PEG molecules per nanoparticle could be separated using gel electrophoresis. Molecules with additional functionalities could be conjugated to the free ends of the bifunctional PEG molecules. In this way the PEG molecules act as convenient spacers that allow for the sorting of nanoparticles with a discrete number of functional groups. (literal)

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