A plant homolog of animal chloride intracellular channels (CLICs) generates an ion conductance in heterologous systems. (Articolo in rivista)

Type

• Articolo in rivista (Classe)
• Prodotto della ricerca (Classe)

Label

• A plant homolog of animal chloride intracellular channels (CLICs) generates an ion conductance in heterologous systems. (Articolo in rivista) (literal)

Anno

• 2007-01-01T00:00:00+01:00 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi

• 10.1074/jbc.M607241200 (literal)

Alternative label

• Elter A; Hartel A; Sieben C; Hertel B; Fischer-Schliebs E; Lüttge U; Moroni A; Thiel G. (2007)
  A plant homolog of animal chloride intracellular channels (CLICs) generates an ion conductance in heterologous systems.
  in The Journal of biological chemistry (Print)
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• Elter A; Hartel A; Sieben C; Hertel B; Fischer-Schliebs E; Lüttge U; Moroni A; Thiel G. (literal)

Pagina inizio

• 8786 (literal)

Pagina fine

• 8792 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 282 (literal)

Rivista

• ?The ?Journal of biological chemistry (Rivista)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo

• 12 (literal)

Note

• ISI Web of Science (WOS) (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• Elter A, Hartel A, Sieben C, Hertel B, Fischer-Schliebs E, Lüttge U, Thiel G.: Institute of Botany, Darmstadt University of Technology, D-64287 Darmstadt, Germany; Moroni A, Thiel Dipartimento di Biologia and IBF-CNR, Universita` degli Studi di Milano, Via Celoria 26, 20133 Milano, Italy (literal)

Titolo

• A plant homolog of animal chloride intracellular channels (CLICs) generates an ion conductance in heterologous systems. (literal)

Abstract

• The genome of Arabidopsis thaliana contains unusual members of the glutathione S-transferase (GST) superfamily with a cysteine in place of a serine at the active site. Four of these genes (at-dhar 1-4) have an appreciable homology to intracellular Cl- channels (CLICs) from vertebrates and invertebrates. Transient expression of AtDHAR1 as wild type protein or as a chimera with GFP in mammalian HEK293 or Chinese hamster ovary cells generated a distinct inward rectifying conductance with a characteristic biphasic kinetics but no apparent ion selectivity. Analysis of the subcellular localization of AtDHRA1::GFP showed that the bulk of the protein was located as soluble form in the cytoplasm; however, an appreciable fraction of it could also be found in association with the non-soluble microsomal fraction. These data suggest that plant members of the GST superfamily have similar to those from animals multiple functions. The increase of ion conductance by AtDHAR1 is better explained by a CLIC-like channel activity than by a modification of endogenous channel proteins. (literal)

Prodotto di

• Istituto di biofisica (IBF) (Istituto)
• Bioenergetica e Biologia molecolare delle piante (MD.P01.005.001) (Modulo)

Autore CNR

• ANNA MORONI (Unità di personale esterno)

Insieme di parole chiave

• Keywords of "A plant homolog of animal chloride intracellular channels (CLICs) generates an ion conductance in heterologous systems." (Insieme di parole chiave)

Incoming links:

Prodotto

• Istituto di biofisica (IBF) (Istituto)
• Bioenergetica e Biologia molecolare delle piante (MD.P01.005.001) (Modulo)

Autore CNR di

• ANNA MORONI (Unità di personale esterno)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• ?The ?Journal of biological chemistry (Rivista)

Insieme di parole chiave di

• Keywords of "A plant homolog of animal chloride intracellular channels (CLICs) generates an ion conductance in heterologous systems." (Insieme di parole chiave)