GABAA receptor subunits identified in Paramecium by immunofluorescence confocal microscopy. (Articolo in rivista)

Type
Label
  • GABAA receptor subunits identified in Paramecium by immunofluorescence confocal microscopy. (Articolo in rivista) (literal)
Anno
  • 2004-01-01T00:00:00+01:00 (literal)
Alternative label
  • Ramoino P., Scaglione S., Diaspro A., Beltrame F., Fato M., Usai C. (2004)
    GABAA receptor subunits identified in Paramecium by immunofluorescence confocal microscopy.
    in FEMS microbiology letters
    (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
  • Ramoino P., Scaglione S., Diaspro A., Beltrame F., Fato M., Usai C. (literal)
Pagina inizio
  • 449 (literal)
Pagina fine
  • 453 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume
  • 238 (literal)
Rivista
Note
  • ISI Web of Science (WOS) (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
  • University of Genoa. CNR, Genoa (literal)
Titolo
  • GABAA receptor subunits identified in Paramecium by immunofluorescence confocal microscopy. (literal)
Abstract
  • The presence of opioid, beta-adrenergic and cholinergic receptors has been demonstrated in ciliated protozoa, but little is known about gamma-aminobutyric acid (GABA) receptors. In this study we have analyzed the distribution of GABA(A)-type receptor subunits in Paramecium. Confocal laser microscopy using antibodies specific for alpha(1)-, alpha(2)-, alpha(3)-, alpha(6)-, beta(2/3)-, gamma(2)-, epsilon-, lambda-, and theta-subunits showed that most receptors are aggregated in clusters and are distributed both on cell surface and in the cytoplasm. The intensity of labelling of the alpha(6)-, beta(2/3)- and gamma(2)-subunits was more intense than the alpha(1)-, epsilon-, and theta-subunits, suggesting that the former are present in higher concentrations than the latter. (literal)
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