A Cdc6-like factor from the archaeon sulfolobus solfataricus promotes binding of MCM to DNA (Articolo in rivista)

Type
Label
  • A Cdc6-like factor from the archaeon sulfolobus solfataricus promotes binding of MCM to DNA (Articolo in rivista) (literal)
Anno
  • 2004-01-01T00:00:00+01:00 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi
  • 10.1074/jbc.M406693200 (literal)
Alternative label
  • De Felice M.; Esposito L.; Pucci B.; De Falco M.; Rossi M.; Pisani F.M. (2004)
    A Cdc6-like factor from the archaeon sulfolobus solfataricus promotes binding of MCM to DNA
    in The Journal of biological chemistry (Print)
    (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
  • De Felice M.; Esposito L.; Pucci B.; De Falco M.; Rossi M.; Pisani F.M. (literal)
Pagina inizio
  • 43008 (literal)
Pagina fine
  • 43012 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume
  • 279 (literal)
Rivista
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo
  • 41 (literal)
Note
  • ISI Web of Science (WOS) (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
  • Istituto di Biochimica delle Proteine, Consiglio Nazionale delle Ricerche, Via P. Castellino 111, 80131-Napoli, Italy (literal)
Titolo
  • A Cdc6-like factor from the archaeon sulfolobus solfataricus promotes binding of MCM to DNA (literal)
Abstract
  • The archaeal replication apparatus appears to be a simplified version of the eukaryotic one with fewer polypeptides and simpler protein complexes. Herein, we report evidence that a Cdc6-like factor from the hyper-thermophilic crenarchaeon Sulfolobus solfataricus stimulates binding of the homo-hexameric MCM-like complex to bubble- and fork-containing DNA oligonucleotides that mimic early replication intermediates. This function does not require the Cdc6 ATP- and DNA-binding activities. These findings may provide important clues to understand how the DNA replication initiation process has evolved in the more complex eukaryotic organisms. (literal)
Prodotto di
Autore CNR

Incoming links:


Autore CNR di
Prodotto
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi
data.CNR.it