ImmunoGrid, an integrative environment for large-scale simulation of the immune system for vaccine discovery, design, and optimization (Articolo in rivista)

Type
Label
  • ImmunoGrid, an integrative environment for large-scale simulation of the immune system for vaccine discovery, design, and optimization (Articolo in rivista) (literal)
Anno
  • 2009-01-01T00:00:00+01:00 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi
  • 10.1093/bib/bbp014 (literal)
Alternative label
  • Pappalardo F.; Halling-Brown M.D.; Rapin N.; Zhang P.; Alemani D.; Emerson A.; Paci P.; Duroux P.; Pennisi M.; Palladini A.; Miotto O.; Churchill D.; Rossi E.; Shepherd A.J.; Moss D.S.; Castiglione F.; Bernaschi M.; Lefranc M-P.; Brunak S.; Motta S.; Lollini P.L.; Bastorfd K.E.; Brusic V. (2009)
    ImmunoGrid, an integrative environment for large-scale simulation of the immune system for vaccine discovery, design, and optimization
    in Briefings in bioinformatics
    (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
  • Pappalardo F.; Halling-Brown M.D.; Rapin N.; Zhang P.; Alemani D.; Emerson A.; Paci P.; Duroux P.; Pennisi M.; Palladini A.; Miotto O.; Churchill D.; Rossi E.; Shepherd A.J.; Moss D.S.; Castiglione F.; Bernaschi M.; Lefranc M-P.; Brunak S.; Motta S.; Lollini P.L.; Bastorfd K.E.; Brusic V. (literal)
Pagina inizio
  • 330 (literal)
Pagina fine
  • 340 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume
  • 10(3) (literal)
Rivista
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo
  • 3 (literal)
Note
  • ISI Web of Science (WOS) (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
  • 1. Univ Queensland, Diamantina Inst Canc Immunol & Metab Med, Brisbane, Qld 4072, Australia 2. CNR, Inst Comp Applicat, Rome, Italy 3. Univ Hong Kong, Fac Educ, Div Informat & Technol Studies, Hong Kong, Hong Kong, Peoples R China 4. Sch Crystallog Birkbeck, Birkbeck, England 5. Univ Roma La Sapienza, Rome, Italy 6. Univ Montpellier 2, F-34095 Montpellier 5, France 7. CNRS, IGM, Inst Human Genet, Immunogenet Mol Lab, F-75700 Paris, France 8. Univ Copenhagen, Ctr Prot Res, Novo Nordisk Fdn, DK-1168 Copenhagen, Denmark 9. Tech Univ Denmark, Dept Syst Biol, Lyngby, Denmark 10. Univ Catania, Fac Pharm, I-95124 Catania, Italy 11. Univ Bologna, I-40126 Bologna, Italy 12. Univ Queensland, Sch Land Crop & Food Sci, Brisbane, Qld 4072, Australia 13. Dana Farber Canc Inst, Canc Vaccine Ctr, Boston, MA 02115 USA (literal)
Titolo
  • ImmunoGrid, an integrative environment for large-scale simulation of the immune system for vaccine discovery, design, and optimization (literal)
Abstract
  • Vaccine research is a combinatorial science requiring computational analysis of vaccine components, formulations and optimization. We have developed a framework that combines computational tools for the study of immune function and vaccine development. This framework, named ImmunoGrid combines conceptual models of the immune system, models of antigen processing and presentation, system-level models of the immune system, Grid computing, and database technology to facilitate discovery, formulation and optimization of vaccines. ImmunoGrid modules share common conceptual models and ontologies. The ImmunoGrid portal offers access to educational simulators where previously defined cases can be displayed, and to research simulators that allow the development of new, or tuning of existing, computational models. The portal is accessible at http://www.w3.org. (literal)
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