Interacting rhythms: possible implication in electrophysiology (Contributo in atti di convegno)

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  • Interacting rhythms: possible implication in electrophysiology (Contributo in atti di convegno) (literal)
Anno
  • 2008-01-01T00:00:00+01:00 (literal)
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  • Cantini F.; Varanini M.; Macerata A.; Piacenti M.; Morales M. A.; Balocchi R. (2008)
    Interacting rhythms: possible implication in electrophysiology
    in Atti Congresso Nazionale di Bioingegneria 2008, Pisa
    (literal)
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  • Cantini F.; Varanini M.; Macerata A.; Piacenti M.; Morales M. A.; Balocchi R. (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#note
  • In: Atti Congresso Nazionale di Bioingegneria 2008 (Pisa, 3-5 Luglio 2008). Atti, pp. 565 - 566. Burattini R., Contro R., Dario P., Landini L (eds.). Patron Editore, 2008. (literal)
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  • ABSTRACT: In the first half of 1980s Leon Glass and co-workers showed that a single brief current pulse delivered to a spontaneously beating cardiac cells aggregate from embryonic chick heart was able to reset the rhythm in a peculiar way depending on both stimulus amplitude and phase of the cycle at which the stimulus was delivered. Furthermore, they showed that a periodic stimulation could lead to synchronization or phase locking between the timulation frequency and the cells cycle [1][2]. Tests on medical devices used to regulate cardiac activity do not usually include an analysis of the effects of these external inputs on the intrinsic physiological rhythms. Our current interest is to investigate through mathematical models and experimental protocols the effects, if present, of this interaction. In particular, our attention is devoted to the effects of the Cardiac Resynchronization Therapy (CRT) to the sinus node rhythm [3]. In this paper we first present the results of a simulation, performed with the aid of a model, aimed at reproducing and extending the Glass experiments, then the results obtained in vivo on subjects under CRT. (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
  • CNR-IFC, Pisa, CNR-IFC, Pisa - Università di Pisa, IFC-CNR - Fondazione G. Monasterio Pisa (literal)
Titolo
  • Interacting rhythms: possible implication in electrophysiology (literal)
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