http://www.cnr.it/ontology/cnr/individuo/prodotto/ID80491

Modeling the temperature rise during diode laser welding of the cornea (Contributo in atti di convegno)

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Modeling the temperature rise during diode laser welding of the cornea (Contributo in atti di convegno) (literal)

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F.Rossi, R.Pini (2005)
Modeling the temperature rise during diode laser welding of the cornea
in Ophthalmic Technologies XV, San Jose, CA, USA
(literal)

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Pubblicato in Ophthalmic Technologies XV, SPIE Vol. 5688, p. 185-193, Bellingham, WA, USA, (2005) (literal)

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ABSTRACT We present the results of a model describing the temperature rise in the cornea during low power diode laser welding of the stroma to induce the repair of corneal wounds. A bi-dimensional model of the anterior segment of the porcine eye was developed. A full thickness corneal cut was considered to be filled by a solution of Indocyanine Green (ICG) in distilled water, which is used to topically enhance the optical absorption of the corneal stroma at the diode laser emission wavelength (810 nm). The typical irradiation conditions used for laser-induced suturing in the transplant of the cornea were considered. The Finite Element Method was used to solve the bio-heat equation inside the cornea wound by using the proper thermal parameters of porcine ocular tissues, providing the thermal response during and shortly after laser treatment. Results indicated a relatively modest temperature increase (DT~ 20 °C), that was spatially confined within the region stained by the chromophore. Calculation of the Arrhenius integral showed no significant thermal damage in the region of the laser-treated wound, thus supporting our previous experimental observations and histological examinations performed on animal models. (literal)

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