Combining experimental evidences from replicates and nearby species data for annotating novel genomes. (Contributo in volume (capitolo o saggio))

Type
Label
  • Combining experimental evidences from replicates and nearby species data for annotating novel genomes. (Contributo in volume (capitolo o saggio)) (literal)
Anno
  • 2008-01-01T00:00:00+01:00 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi
  • 10.1063/1.2965094 (literal)
Alternative label
  • C. Angelini, L. Cutillo, I. De Feis, R. van der Wath, P. Lio’ (2008)
    Combining experimental evidences from replicates and nearby species data for annotating novel genomes.
    in AIP Conference Proceedings, 2008
    (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
  • C. Angelini, L. Cutillo, I. De Feis, R. van der Wath, P. Lio’ (literal)
Pagina inizio
  • 277 (literal)
Pagina fine
  • 291 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#altreInformazioni
  • COLLECTIVE DYNAMICS: TOPICS ON COMPETITION AND COOPERATION IN THE BIOSCIENCES: A Selection of Papers in the Proceedings of the BIOCOMP2007 International Conference (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#url
  • http://proceedings.aip.org/resource/2/apcpcs/1028/1?isAuthorized=no (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#titoloVolume
  • AIP Conference Proceedings (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume
  • 1028 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#volumeInCollana
  • 1028 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#note
  • In COLLECTIVE DYNAMICS: TOPICS ON COMPETITION AND COOPERATION IN THE BIOSCIENCES: A Selection of Papers in the Proceedings of the BIOCOMP2007 International Conference, AIP Proceedings, Vol. 1028, (2008). (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#pagineTotali
  • 15 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
  • Istituto per le Applicazioni del Calcolo ``Mauro Picone'' (CNR), Napoli, Italia Computer Laboratory, University of Cambridge, Cambridge, Regno Unito Telethon Institute of Genetics and Medicine, Napoli, Italia (literal)
Titolo
  • Combining experimental evidences from replicates and nearby species data for annotating novel genomes. (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#isbn
  • 978-0-7354-0552-3 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#curatoriVolume
  • Luigi M. Ricciardi, Aniello Buonocore, Enrica Pirozzi (literal)
Abstract
  • For several years now, there has been an exponential growth of the amount of life science data (e.g., sequenced complete genomes, 3D structures, DNA chips, Mass spectroscopy data) generated by high throughput experiments. Carrying out analyses of complex, voluminous, and heterogeneous data and guiding the analysis of data using a statistical and mathematical sound methodology is thus of paramount importance. Here we make and justify the observation that experimental replicates and phylogenetic data may be combined to strength the evidences on identifying transcriptional motifs, which seems to be quite difficult using other currently used methods. We present a case study considering sequences and microarray data from fungi species. Although we show that our methodology can result of immediate practical utility to bioinformaticians and biologists for annotating new genomes, here the focus is also on discussing the dependent interesting mathematical problems that high throughput data integration poses. (literal)
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