Modelling cell populations with spatial structure: steady state and treatment-induced evolution of tumour cords (Articolo in rivista)

Type

• Prodotto della ricerca (Classe)
• Articolo in rivista (Classe)

Label

• Modelling cell populations with spatial structure: steady state and treatment-induced evolution of tumour cords (Articolo in rivista) (literal)

Anno

• 2004-01-01T00:00:00+01:00 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi

• 10.3934/dcdsb.2004.4.161 (literal)

Alternative label

• Alessandro Bertuzzi (a); Alberto d'Onofrio (a, b); Alberto d'Onofrio (c); Alberto Gandolfi (a) (2004)
  Modelling cell populations with spatial structure: steady state and treatment-induced evolution of tumour cords
  in Discrete and continuous dynamical systems. Series B (Online)
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• Alessandro Bertuzzi (a); Alberto d'Onofrio (a, b); Alberto d'Onofrio (c); Alberto Gandolfi (a) (literal)

Pagina inizio

• 161 (literal)

Pagina fine

• 186 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 4 (literal)

Rivista

• Discrete and continuous dynamical systems. Series B (Rivista)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo

• 1 (literal)

Note

• Scopu (literal)
• ISI Web of Science (WOS) (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• a. Istituto di Analisi dei Sistemi ed Informatica \"A. Ruberti\" - CNR b. European Institute of Oncology - Division of Epidemiology and Biostatistics c. Dipartimento di Matematica \"Ulisse Dini\" - Università degli studi di Firenze (literal)

Titolo

• Modelling cell populations with spatial structure: steady state and treatment-induced evolution of tumour cords (literal)

Abstract

• Tumour cells growing around blood vessels form structures called tumour cords. We review some mathematical models that have been proposed to describe the stationary state of the cord and the cord evolution after single-dose cell killing treatment. Whereas the cell population has been represented with age or maturity structure to describe the cord stationary state, for the response to treatment a simpler approach was followed, by representing the cell population by means of the cell volume fractions. In this latter model, where transport of oxygen is included and its concentration is critical for cell viability, some constraints to be imposed on the interface separating the tumour from the necrotic region have a crucial role. An analysis of experimental data from untreated tumour cords, which involves modelling by cell age and by volume fractions, and some results about the cord response to impulsive cell killing, are also presented. (literal)

Prodotto di

• Modelli e Metodi Matematici in Fisiopatologia (ME.P06.002.001) (Modulo)
• Istituto di analisi dei sistemi ed informatica \"Antonio Ruberti\" (IASI) (Istituto)

Autore CNR

• ALBERTO D'ONOFRIO (Unità di personale esterno)
• ALESSANDRO BERTUZZI (Unità di personale interno)
• ALBERTO GANDOLFI (Unità di personale interno)

Insieme di parole chiave

• Parole chiave di "Modelling cell populations with spatial structure: steady state and treatment-induced evolution of tumour cords" (Insieme di parole chiave)

Incoming links:

Autore CNR di

• ALBERTO GANDOLFI (Unità di personale interno)
• ALESSANDRO BERTUZZI (Unità di personale interno)
• ALBERTO D'ONOFRIO (Unità di personale esterno)

Prodotto

• Istituto di analisi dei sistemi ed informatica \"Antonio Ruberti\" (IASI) (Istituto)
• Modelli e Metodi Matematici in Fisiopatologia (ME.P06.002.001) (Modulo)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• Discrete and continuous dynamical systems. Series B (Rivista)

Insieme di parole chiave di

• Parole chiave di "Modelling cell populations with spatial structure: steady state and treatment-induced evolution of tumour cords" (Insieme di parole chiave)