Repertoire Of Gluten Peptides Active In Celiac Disease Patients: Perspectives For Translational Therapeutic Applications (Articolo in rivista)

Type

• Prodotto della ricerca (Classe)
• Articolo in rivista (Classe)

Label

• Repertoire Of Gluten Peptides Active In Celiac Disease Patients: Perspectives For Translational Therapeutic Applications (Articolo in rivista) (literal)

Anno

• 2012-01-01T00:00:00+01:00 (literal)

Alternative label

• Camarca A; Del Mastro A; Gianfrani C (2012)
  Repertoire Of Gluten Peptides Active In Celiac Disease Patients: Perspectives For Translational Therapeutic Applications
  in Endocrine, metabolic & immune disorders. Drug targets (Print)
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• Camarca A; Del Mastro A; Gianfrani C (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 12 (literal)

Rivista

• Endocrine, metabolic & immune disorders. Drug targets (Rivista)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• Institute of Food Sciences-CNR, Avellino, Italy, European Laboratory for the Investigation of Food-Induced Diseases, University \"Federico II\" of Naples, Italy (literal)

Titolo

• Repertoire Of Gluten Peptides Active In Celiac Disease Patients: Perspectives For Translational Therapeutic Applications (literal)

Abstract

• Celiac disease is a common and lifelong food intolerance, affecting approximately 1% of the population. Because of a mechanism not completely understood, the ingestion of wheat gluten, and of homologue proteins of barley and rye, induces in genetically predisposed individuals pronounced inflammatory reactions mainly at the site of small intestine. Gluten, the triggering factor, is a complex protein mixture highly resistant to the gastrointestinal enzymatic proteolysis, and this results in the presence of large, and potentially immunogenic, peptides at the intestinal mucosa surface. During the last decade, several studies have defined gluten peptides able to stimulate adaptive T cells, of either CD4 or CD8 phenotype, and to activate innate (non T) immune cells. This review examines the complete repertoire of gluten peptides recognized by celiac T cells and discusses the several translational implications that the identification of these epitopes opens. (literal)

Prodotto di

• Bioassay cellulari per l’analisi della proprietà immunostimolanti degli alimenti (AG.P05.005.008) (Modulo)
• Alimenti e salute dell'uomo (AG.P05.005.001) (Modulo)
• Institute of food sciences (ISA) (Istituto)

Autore CNR

• CARMELA GIANFRANI (Unità di personale interno)

Incoming links:

Prodotto

• Institute of food sciences (ISA) (Istituto)
• Alimenti e salute dell'uomo (AG.P05.005.001) (Modulo)
• Bioassay cellulari per l’analisi della proprietà immunostimolanti degli alimenti (AG.P05.005.008) (Modulo)

Autore CNR di

• CARMELA GIANFRANI (Unità di personale interno)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• Endocrine, metabolic & immune disorders. Drug targets (Rivista)