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Evaluation of the efficacy of the italian guidelines on COPD: a cluster randomized trial (Articolo in rivista)

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Evaluation of the efficacy of the italian guidelines on COPD: a cluster randomized trial (Articolo in rivista) (literal)

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C. Tinelli, C. Rezzani, G. Biino, A. Marinoni, A. Rossi, E. Volpini, A. Pistorio, R. Termini, M. Grassi. (2003)
Evaluation of the efficacy of the italian guidelines on COPD: a cluster randomized trial
in Monaldi archives for chest disease
(literal)

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C. Tinelli, C. Rezzani, G. Biino, A. Marinoni, A. Rossi, E. Volpini, A. Pistorio, R. Termini, M. Grassi. (literal)

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° Servizio di Epidemiologia Clinica e Biometria I.R.C.C.S. Policlinico San Matteo, Pavia. § Dipartimento di Scienze Sanitarie Applicate, Università di Pavia. * Divisione di Pneumologia I.R.C.C.S Policlinico San Matteo, Pavia. ^ Health Care Affaire - Boehringer Ingelheim, Italia, Milano. (literal)

Titolo

Evaluation of the efficacy of the italian guidelines on COPD: a cluster randomized trial (literal)

Abstract

Question of the study. Chronic Obstructive Pulmonary Disease (COPD) is a profoundly disabling disease managed predominantly by General Practitioners (GPs). We planned this prospective trial to evaluate the applicability of Italian GP-directed guidelines in routine practice and whether adherence to them improves treatment efficacy, with respect to decreased exacerbations, hospital admissions, drug use, and out-patient appointments and improved quality of life (QoL). Materials and methods. In a cluster randomised trial, 22 GPs were randomly put into two groups: one group was asked to follow the guidelines (YES-GL), the other to continue normal clinical practice (NO-GL). These GPs enrolled 123 patients with COPD and followed them for one year. Results. Patients managed by the YES-GL GPs had more outpatient appointments and specialist consultations and a higher probability of being classified as having severe COPD. The QoL was fairly low in both groups, and all other clinical outcomes taken into consideration, were not affected by application of the guidelines. Answer to the question. In conclusion, the guidelines did not substantially alter the clinical evolution of COPD patients, even though some facets of management improved (literal)

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