http://www.cnr.it/ontology/cnr/individuo/prodotto/ID62747
Emergency surgical procedure for failed methotrexate treatment of cervical pregnancy: A case report (Articolo in rivista)
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- Emergency surgical procedure for failed methotrexate treatment of cervical pregnancy: A case report (Articolo in rivista) (literal)
- Anno
- 2007-01-01T00:00:00+01:00 (literal)
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- Tinelli A.; Malvasi A.; Vergara D.; Casciaro S. (literal)
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- In: The European Journal of Contraception and Reproductive Health Care, vol. 0 pp. 1 - 5. DEJC_A_250105. Parthenon Publishing Group, 2007. (literal)
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- Department of Obstetrics and Gynaecology, 'Vito Fazzi' Hospital, Lecce; Department of Obstetrics and Gynaecology, 'Santa Maria' Hospital, Bari; National Nanotechnology Laboratory (NNL), CNR-INFM, University of Lecce; Biomedical Engineering Science and Technology Division, IFC-CNR, Institute of Clinical Physiology, National Council of Research, Italy (literal)
- Titolo
- Emergency surgical procedure for failed methotrexate treatment of cervical pregnancy: A case report (literal)
- Abstract
- Cervical pregnancy (CP) is a rare and dangerous condition, which may cause a massive haemorrhage. Ultrasonographic diagnosis consists of the visualization of the gestational sac and trophoblastic invasion in an endocervical localization. CP treatment modalities include dilatation and curettage (D&C) usually followed by intracervical tamponade, cervicotomy, angiographic embolization, ligation of the uterine arteries, and chemotherapy with methotrexate (MTX). MTX administration is a very appealing therapeutic modality of CP in the first trimester because of its convenience and efficacy. We report a case of unsuccessful treatment of a CP with systemic MTX administration, which led to an emergency surgical procedure for a sudden massive vaginal haemorrhage. A vaginal ligation of the cervical branches of the uterine arteries was carried out, followed by suction curettage, D&C and insertion of an intrauterine sterile tampon that was removed after 48 hours. The patient did not require a blood transfusion. Histological examination of the specimen confirmed the CP. (literal)
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