Cardiac production of C-type natriuretic peptide in heart failure (Articolo in rivista)

Type

• Prodotto della ricerca (Classe)
• Articolo in rivista (Classe)

Label

• Cardiac production of C-type natriuretic peptide in heart failure (Articolo in rivista) (literal)

Anno

• 2006-01-01T00:00:00+01:00 (literal)

Alternative label

• Del Ry S.; Maltinti M.; Piacenti M.; Passino C.; Emdin M.; Giannessi D. (2006)
  Cardiac production of C-type natriuretic peptide in heart failure
  in Journal of cardiovascular medicine (Hagerstown, Md. : Online)
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• Del Ry S.; Maltinti M.; Piacenti M.; Passino C.; Emdin M.; Giannessi D. (literal)

Pagina inizio

• 397 (literal)

Pagina fine

• 399 (literal)

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• 7 (literal)

Rivista

• Journal of cardiovascular medicine (Rivista)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#note

• In: Journal of Cardiovascular Medicine, vol. 7 (6) pp. 397-399. Lippincot, 2006. (literal)

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• Institute of Clinical Physiology, National Research Council, Pisa, Italy. (literal)

Titolo

• Cardiac production of C-type natriuretic peptide in heart failure (literal)

Abstract

• BACKGROUND: C-type natriuretic peptide production by the heart in patients with chronic heart failure has recently been demonstrated by measuring the difference in C-type natriuretic peptide plasma levels between the aortic root and coronary sinus samples. To assess this previous relevant observation, we re-evaluated the cardiac production of C-type natriuretic peptide, thus increasing the total number of patients studied. In light of the difficulty in recruiting patients with these characteristics, this kind of study can be performed with a small number of subjects. METHODS: Cardiac production of C-type natriuretic peptide was evaluated in a subset (n = 6) of patients, referred to our institute for the evaluation of chronic heart failure. C-type natriuretic peptide was measured in the coronary sinus and in aorta blood collected during right and left heart catheterization using a specific immunometric assay, after solid-phase extraction of plasma samples. RESULTS: Significantly higher C-type natriuretic peptide levels were found in the coronary sinus than in aorta blood (7.8 +/- 1.3 versus 6.1 +/- 1.5 pg/ml, P = 0.034) and our results were in accordance with previous ones. Analysing as a whole the data gathered in the two studies, a noteworthy significant increase was observed (n = 15, P = 0.002) between the C-type natriuretic peptide concentrations in the two sites. CONCLUSIONS: The results of the present study strengthen the hypothesis that C-type natriuretic peptide is produced by the heart in patients with chronic heart failure. (literal)

Prodotto di

• Tassonomia clinica molecolare - Tassonomia clinica molecolare (ME.P05.003.001) (Modulo)
• Istituto di fisiologia clinica (IFC) (Istituto)

Autore CNR

• MARISTELLA MALTINTI (Persona)
• MICHELE EMDIN (Unità di personale esterno)
• SILVIA DEL RY (Unità di personale interno)
• DANIELA GIANNESSI (Unità di personale interno)
• CLAUDIO PASSINO (Unità di personale interno)

Insieme di parole chiave

• Parole chiave di "Cardiac production of C-type natriuretic peptide in heart failure" (Insieme di parole chiave)

Incoming links:

Autore CNR di

• DANIELA GIANNESSI (Unità di personale interno)
• SILVIA DEL RY (Unità di personale interno)
• CLAUDIO PASSINO (Unità di personale interno)
• MARISTELLA MALTINTI (Persona)
• MICHELE EMDIN (Unità di personale esterno)

Prodotto

• Istituto di fisiologia clinica (IFC) (Istituto)
• Tassonomia clinica molecolare - Tassonomia clinica molecolare (ME.P05.003.001) (Modulo)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• Journal of cardiovascular medicine (Rivista)

Insieme di parole chiave di

• Parole chiave di "Cardiac production of C-type natriuretic peptide in heart failure" (Insieme di parole chiave)