The bromodomain: a chromatin browser? (Articolo in rivista)

  • The bromodomain: a chromatin browser? (Articolo in rivista) (literal)
  • 2001-01-01T00:00:00+01:00 (literal)
Alternative label
  • Filetici P. 1, Ornaghi P. 2, Ballario P., 2 (2001)
    The bromodomain: a chromatin browser?
  • Filetici P. 1, Ornaghi P. 2, Ballario P., 2 (literal)
Pagina inizio
  • D866 (literal)
Pagina fine
  • D876 (literal)
  • The general interest and impact of this research will be possibly related to the study of human malignancies for the design of valuable cytostatic molecules. The citations record accounts for a wide interdisciplinary interest for this topic and this article. ISI Web of Science, Cited References: 2002 Cur. Opin. Emathology, Mol. Cell. Biol., J. Biol. Chem.; 2003 Gen. Dev., J. of Virology, Nuc. Ac. Res., Biochem. J., 2004 Blood, Mol. Cell. Biol. The review is published in a peer-reviewed international journal with an impact factor of 3.063. (literal)
  • 6 (literal)
  • P. Ballario รจ a disposizione dell'IBPM (literal)
  • The Bromodomain is an evolutionary conserved domain found in almost all the histone acetyltransferases and chromatin proteins. We discovered its function of histone interactor and its binding specificity for acetyl-lysine. The review deals with the widespread conservation of the macromolecular structure and function of bromodomain motif and the biological relevance of the bromodomain-proteins in human malignancies like leukemia and lymphoma. Issued in 2001 volume of Frontiers in Bioscience: The role of bromodomain proteins in the cell cycle and cancer. (literal)
  • 1 CNR (C.S. sugli Acidi Nucleici), 2 UNI Sapienza (Dipartimento di Genetica e Biologia Molecolare). (literal)
  • The bromodomain: a chromatin browser? (literal)
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