Differentiation of human LAN-5 neuroblastoma cells induced by extremely low frequency electronically transmitted retinoic acid. (Articolo in rivista)

Type
Label
  • Differentiation of human LAN-5 neuroblastoma cells induced by extremely low frequency electronically transmitted retinoic acid. (Articolo in rivista) (literal)
Anno
  • 2011-01-01T00:00:00+01:00 (literal)
Alternative label
  • Foletti Alberto, Ledda Mario, D'Emilia Enrico, Grimaldi Settimio, Lisi Antonella. (2011)
    Differentiation of human LAN-5 neuroblastoma cells induced by extremely low frequency electronically transmitted retinoic acid.
    in Journal of alternative and complementary medicine (N.Y. N.Y., Online)
    (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
  • Foletti Alberto, Ledda Mario, D'Emilia Enrico, Grimaldi Settimio, Lisi Antonella. (literal)
Pagina inizio
  • 701 (literal)
Pagina fine
  • 704 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume
  • 17 (literal)
Rivista
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#pagineTotali
  • 4 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo
  • 8 (literal)
Note
  • ISI Web of Science (WOS) (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
  • Bititalia, Milan, Italy. Institute of Neurobiology and Molecular Medicine, National Research Council, Rome, Italy. Institute for Workers Safety, Rome, Italy. (literal)
Titolo
  • Differentiation of human LAN-5 neuroblastoma cells induced by extremely low frequency electronically transmitted retinoic acid. (literal)
Abstract
  • BACKGROUND: Jaques Benveniste suggested that electronic transmission of 4-phorbol-12-b-myristate-13-acetate (PMA) activity, carried out using a simple amplifier configured to function as an oscillator when coupled to two electromagnetic coils, demonstrates the same chemical activity as the active molecule. The results obtained suggested that there are associated signals at the PMA molecules that can be transferred to target neutrophils by artificial physical means in a fashion that mimics the original molecules. METHODS: Retinoic acid was placed at room temperature on one coil attached to an oscillator (VEGA select 719), while LAN-5 neuroblastoma cells were placed on another coil and incubated under controlled condition. The oscillator was then turned on for 12 hours a day for 5 days, after which cells were counted and morphology studied by contrast microscopy. RESULTS: The effect of the differentiating agent added to the cell culture by physical means generates a decrease in cell growth, metabolic activity, and the protrusion of a neuritelike structure typical of the differentiated cells. CONCLUSIONS: These preliminary results suggest that retinoic acid molecules emit signals that can be transferred to LAN-5 neuroblastoma cells by artificial physical means in a manner that seems related to the chemical structure of the source molecules. (literal)
Prodotto di
Autore CNR

Incoming links:


Autore CNR di
Prodotto
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi
data.CNR.it