Highly electroconductive multiwalled carbon nanotubes as potentially useful tools for modulating calcium balancing in biological environments. (Articolo in rivista)

Type

• Prodotto della ricerca (Classe)
• Articolo in rivista (Classe)

Label

• Highly electroconductive multiwalled carbon nanotubes as potentially useful tools for modulating calcium balancing in biological environments. (Articolo in rivista) (literal)

Anno

• 2012-01-01T00:00:00+01:00 (literal)

Alternative label

• Serafino A, Togna AR, Togna GI, Lisi A, Ledda M, Grimaldi S, Russier J, Andreola F, Monthioux M, Béguin F, Marcaccio M, Rapino S, Paolucci F, Fiorito S. (2012)
  Highly electroconductive multiwalled carbon nanotubes as potentially useful tools for modulating calcium balancing in biological environments.
  in Nanomedicine (Lond., Print)
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• Serafino A, Togna AR, Togna GI, Lisi A, Ledda M, Grimaldi S, Russier J, Andreola F, Monthioux M, Béguin F, Marcaccio M, Rapino S, Paolucci F, Fiorito S. (literal)

Pagina inizio

• 299 (literal)

Pagina fine

• 307 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 8 (literal)

Rivista

• Nanomedicine (Rivista)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo

• 3 (literal)

Note

• ISI Web of Science (WOS) (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• a. Institute of Translational Pharmacology - CNR, Rome, Italy b. Dept of Physiology and Pharmacology, University La Sapienza, Rome, Italy c. CEMES, UPR 8011 CNRS, Toulouse, France d. CRMD, CNRS-University, Orléans, France e. Dept of Chemistry \"G. Ciamician\", Bologna University, Italy (literal)

Titolo

• Highly electroconductive multiwalled carbon nanotubes as potentially useful tools for modulating calcium balancing in biological environments. (literal)

Abstract

• Aiming to explore the mechanisms modulating cell-carbon nanotube interactions, we investigated whether Ca(2+) ion balancing between intra- and extracellular environments could be affected by multiwalled carbon nanotubes (MWCNTs). We analyzed the effects induced by two different kinds of MWCNTs (as prepared and annealed at 2400°C) on the intracellular Ca(2+) ion levels in rat electrically sensitive cells and on the intercellular junction integrity of rat adenocarcinoma colon cells and platelet aggregation ability, which depend on the Ca(2+) concentration in the medium. MWCNTs, purified by annealing and more electroconductive as compared to nonannealed MWCNTs, affected Ca(2+) ion balancing between extra- and intracellular environments and induced changes on Ca(2+) ion-dependent cellular junctions and platelet aggregation, behaving as the calcium chelator ethylene glycol tetraacetic acid. This could be due to the sorption of cationic Ca(2+) ions on CNTs surface because of the excess of negatively charged electrons on the aromatic units formed on MWCNTs after annealing. (literal)

Prodotto di

• Target molecolari, modelli preclinici ed immunoterapia in Oncologia (ME.P03.015.001) (Modulo)
• Sviluppo di protocolli per il differenziamento di cellule staminali tramite interazione tra frequenze di risonanza di ciclotrone di ioni e biosistemi (ME.P06.031.003) (Modulo)
• La Risonanza di ciclotrone come strategia per la veicolazione e il rilascio di farmaci (ME.P06.031.001) (Modulo)

Autore CNR

• SETTIMIO GRIMALDI (Persona)
• FEDERICA ANDREOLA (Persona)
• ANNALUCIA SERAFINO (Persona)
• SILVANA FIORITO (Persona)
• MARIO LEDDA (Persona)
• ANTONELLA LISI (Unità di personale interno)

Incoming links:

Autore CNR di

• ANTONELLA LISI (Unità di personale interno)
• MARIO LEDDA (Persona)
• ANNALUCIA SERAFINO (Persona)
• SETTIMIO GRIMALDI (Persona)
• SILVANA FIORITO (Persona)
• FEDERICA ANDREOLA (Persona)

Prodotto

• La Risonanza di ciclotrone come strategia per la veicolazione e il rilascio di farmaci (ME.P06.031.001) (Modulo)
• Target molecolari, modelli preclinici ed immunoterapia in Oncologia (ME.P03.015.001) (Modulo)
• Sviluppo di protocolli per il differenziamento di cellule staminali tramite interazione tra frequenze di risonanza di ciclotrone di ioni e biosistemi (ME.P06.031.003) (Modulo)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• Nanomedicine (Rivista)