Management of metabolic syndrome in children and adolescents (Articolo in rivista)

Type
Label
  • Management of metabolic syndrome in children and adolescents (Articolo in rivista) (literal)
Anno
  • 2011-01-01T00:00:00+01:00 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi
  • 10.1016/j.numecd.2011.01.011 (literal)
Alternative label
  • L. Pacifico, C. Anania, F. Martino, E. Poggiogalle, F. Chiarelli, M. Arca, C. Chiesa (2011)
    Management of metabolic syndrome in children and adolescents
    in NMCD. Nutrition Metabolism and Cardiovascular Diseases (Testo stamp.); Medikal Press, Milano (Italia)
    (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
  • L. Pacifico, C. Anania, F. Martino, E. Poggiogalle, F. Chiarelli, M. Arca, C. Chiesa (literal)
Pagina inizio
  • 455 (literal)
Pagina fine
  • 466 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume
  • 21 (literal)
Rivista
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#pagineTotali
  • 12 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo
  • 6 (literal)
Note
  • Scopu (literal)
  • ISI Web of Science (WOS) (literal)
  • ubMe (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
  • 1. L. Pacifico, C. Anania, F. Martino, E. Poggiogalle: Department of Pediatrics,Sapienza University of Rome, Italy 2. F.Chiarelli:Department of Pediatrics, University of Chieti, Italy 3. M.Arca: Department of Internal Medicine and Allied Specialities,Sapienza University of Rome, Italy 4. C.Chiesa: Institute of Translational Pharmacology, National Research Council, Italy (literal)
Titolo
  • Management of metabolic syndrome in children and adolescents (literal)
Abstract
  • Concomitantly with the increasing prevalence of childhood obesity, the prevalence of metabolic syndrome (MS) is rising among children and adolescents, leading to fears forfuture epidemics of type 2 diabetes mellitus and cardiovascular disease in the young. This makes the accurate identification and the appropriate treatment of children and adolescents with MS an important priority for health care systems. This review will focus on the management of each component of MS, including the nonalcoholic fatty liver disease (NAFLD), which is currently considered as the hepatic component of the syndrome. The most relevant target of treatment of MS in children and adolescents is the abdominal obesity. To this end, we will discuss the efficacy of dietary approaches, possibly coupled with regular physical activity, on eliciting visceral fat reduction. We will also highlight several aspects of the treatment of the high triglyceride/low high-density lipoprotein cholesterol phenotype, including the use of non-pharmacological measures, and indications for instituting drug therapies. Part of this review will address treatment of glucose abnormalities, including the benefits of lifestyle modification alone, and the potential adjunctive role of hypoglycemic drugs. The treatment of hypertension in children with MS also requires a multifaceted approach and the available data of this topic will be examined. The remainder of this review will address treatment to reverse NAFLD and prevent progression to end-stage disease. (literal)
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