EIS microfluidic chips for flow immunoassay and ultrasensitive cholera toxin detection (Articolo in rivista)

Type
Label
  • EIS microfluidic chips for flow immunoassay and ultrasensitive cholera toxin detection (Articolo in rivista) (literal)
Anno
  • 2011-01-01T00:00:00+01:00 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi
  • 10.1039/c0lc00409j (literal)
Alternative label
  • M. S. Chiriacò; E. Primiceri; E. D'Amone; R. E. Ionescu; R. Rinaldi; G. Maruccio (2011)
    EIS microfluidic chips for flow immunoassay and ultrasensitive cholera toxin detection
    in Lab on a chip (Print)
    (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
  • M. S. Chiriacò; E. Primiceri; E. D'Amone; R. E. Ionescu; R. Rinaldi; G. Maruccio (literal)
Pagina inizio
  • 658 (literal)
Pagina fine
  • 663 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#url
  • http://dx.doi.org/10.1039/c0lc00409j (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume
  • 11 (literal)
Rivista
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#note
  • DOI: 10.1039/c0lc00409j Acknowledgment:This work was partially supported by the Italian Institute of Technology (IIT) and by MIUR FIRB Project No. BNE03FMCJ_003. (literal)
Note
  • Scopus (literal)
  • ISI Web of Science (WOS) (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
  • 1. NNL CNR Ist Nanosci, Lecce, Italy (M.S. Chiriaco, E. Primiceri, E. D'Amone, R. Rinaldi, G. Maruccio) 2. Univ Salento, Scuola Super ISUFI, Lecce, Italy (M.S. Chiriaco, E. Primiceri, R.E. Ionescu) 3. Univ Salento, Dept Innovat Engn, Lecce, Italy (R. Rinaldi) 4. Univ Salento, Dept Phys, Lecce, Italy (G. Maruccio) (literal)
Titolo
  • EIS microfluidic chips for flow immunoassay and ultrasensitive cholera toxin detection (literal)
Abstract
  • A flow-injection impedimetric immunosensor for the sensitive, direct and label-free detection of cholera toxin is reported. Alimit of detection smaller than 10 pM was achieved, a value thousands of times lower than the lethal dose. The developed chips fulfil the requirement of low cost and quick reply of the assay and are expected to enable field screening, prompt diagnosis and medical intervention without the need of specialized personnel and expensive equipment, a perspective of special relevance for use in developing countries. Since the chip layout includes two sensing areas each one with a 2 x 2 sensor array, our biochips can allow statistical or (alternatively) multiplex analysis of biorecognition events between antibodies immobilized on each working electrode and different antigens flowing into the chamber. (literal)
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