http://www.cnr.it/ontology/cnr/individuo/prodotto/ID59118
Drug-loaded polyelectrolyte microcapsules for sustained targeting of cancer cells (Articolo in rivista)
- Type
- Label
- Drug-loaded polyelectrolyte microcapsules for sustained targeting of cancer cells (Articolo in rivista) (literal)
- Anno
- 2011-01-01T00:00:00+01:00 (literal)
- Alternative label
Vergaro V., F. Scarlino, C. Bellomo, R. Rinaldi, D. Vergara, M. Maffia, F. Baldassarre, G. Giannelli, X. Zhang, Y. M. Lvov, and S. Leporatti (2011)
Drug-loaded polyelectrolyte microcapsules for sustained targeting of cancer cells
in Advanced drug delivery reviews
(literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
- Vergaro V., F. Scarlino, C. Bellomo, R. Rinaldi, D. Vergara, M. Maffia, F. Baldassarre, G. Giannelli, X. Zhang, Y. M. Lvov, and S. Leporatti (literal)
- Pagina inizio
- Pagina fine
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume
- Rivista
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#note
- DOI: 10.1016/j.addr.2011.05.007 (literal)
- Note
- ISI Web of Science (WOS) (literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
- CNR-Instituto Nanoscienze, NNL Via Arnesano 16, 73100 Lecce (Italy)
Department of Biological and Environmental Sciences and Technologies (DiSteBA), University of Salento, Ecotekne, SP Lecce - Monteroni 73100 Lecce (Italy)
Department of Internal Medicine, Immunology and Infectious Diseases, Section of Internal Medicine, University of Bari, Medical School, Bari (Italy)
Institute for Micromanufacturing of Louisiana Tech University, 911 Hergot Ave, Ruston, LA 71272, USA (literal)
- Titolo
- Drug-loaded polyelectrolyte microcapsules for sustained targeting of cancer cells (literal)
- Abstract
- In this review we will overview novel nanotechnological nanocarrier systems for cancer therapy focusing on recent development in polyelectrolyte capsules for targeted delivery of antineoplastic drugs against cancer cells. Biodegradable polyelectrolyte microcapsules (PMCs) are supramolecular assemblies of particular interest for therapeutic purposes, as they can be enzymatically degraded into viable cells, under physiological conditions. Incorporation of small bioactive molecules into nano-to-microscale delivery systems may increase drug's bioavailability and therapeutic efficacy at single cell level giving desirable targeted therapy. Layer-by-layer (LbL) self-assembled PMCs are efficient microcarriers that maximize drug's exposure enhancing antitumor activity of neoplastic drug in cancer cells. They can be envisaged as novel multifunctional carriers for resistant or relapsed patients or for reducing dose escalation in clinical settings. (literal)
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- Autore CNR
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