Antioxidant activity of galloyl quinic derivatives isolated from P. lentiscus leaves. (Articolo in rivista)

Type
Label
  • Antioxidant activity of galloyl quinic derivatives isolated from P. lentiscus leaves. (Articolo in rivista) (literal)
Anno
  • 2003-01-01T00:00:00+01:00 (literal)
Alternative label
  • Baratto MC., Tattini M., Galardi C., Pinelli P., Romani A., Visioli F., Basosi R., Pogni R. (2003)
    Antioxidant activity of galloyl quinic derivatives isolated from P. lentiscus leaves.
    in Free radical research
    (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
  • Baratto MC., Tattini M., Galardi C., Pinelli P., Romani A., Visioli F., Basosi R., Pogni R. (literal)
Pagina inizio
  • 405 (literal)
Pagina fine
  • 412 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume
  • 37 (literal)
Rivista
Note
  • ISI Web of Science (WOS) (literal)
Titolo
  • Antioxidant activity of galloyl quinic derivatives isolated from P. lentiscus leaves. (literal)
Abstract
  • The antioxidant properties of galloyl quinic derivatives isolated from Pistacia lentiscus L leaves have been investigated by means of Electronic Paramagnetic Resonance spectroscopy (EPR) and UV-Vis spectrophotometry. Antioxidant properties have been also estimated using the biologically relevant LDL test. The scavenger activities of gallic acid, 5-O-galloyl, 3,5 di-O-galloyl, 3,4,5 tri-O-galloyl quinic acid derivatives, have been estimated against 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical, superoxide (O2-) radical, and hydroxyl (OH) radical. On the whole scavenger activity raised as the number of galloyl groups on the quinic acid skeleton increased. The half-inhibition concentration (IC50) of di- and tri-galloyl derivatives did not exceed 30 micromolar for all the tested free radiacls. All the tested metabolites strongly reduced the oxidation of low-density lipoproteins (LDL), following a trend similar to that observed for the scavenger ability against OH radical. (literal)
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