Neuromelanins in various regions of human brain are associated with native and oxidized isoprenoid lipids. (Articolo in rivista)

Type

• Articolo in rivista (Classe)
• Prodotto della ricerca (Classe)

Label

• Neuromelanins in various regions of human brain are associated with native and oxidized isoprenoid lipids. (Articolo in rivista) (literal)

Anno

• 2009-01-01T00:00:00+01:00 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi

• 10.1016/j.abb.2009.01.013 (literal)

Alternative label

• Ward W.C.; Zucca F.A.; Bellei C.; Zecca L.; Simon J.D. (2009)
  Neuromelanins in various regions of human brain are associated with native and oxidized isoprenoid lipids.
  in Archives of biochemistry and biophysics (Print)
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• Ward W.C.; Zucca F.A.; Bellei C.; Zecca L.; Simon J.D. (literal)

Pagina inizio

• 94 (literal)

Pagina fine

• 99 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 484 (literal)

Rivista

• Archives of biochemistry and biophysics (Rivista)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo

• 1 (literal)

Note

• ISI Web of Science (WOS) (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• Department of Chemistry, Duke University, Durham, NC, USA; Institute of Biomedical Technologies, Italian National Research Council, Segrate, Italy. (literal)

Titolo

• Neuromelanins in various regions of human brain are associated with native and oxidized isoprenoid lipids. (literal)

Abstract

• Neuromelanin (NM) isolated from seven regions of the human brain is found to contain series of natural and oxidized isoprenoid lipids. Specifically, dolichols (dol) and dolichoic acids (dol-CA) with 14-22 and 14-21 isoprene units are identified. Standards of nor-dolichol and nor-dolichoic acid were used to determine the relative amounts of dol and dol-CA compared to the total lipids present in NM for each region. The cerebellum, putamen, globus pallidus, and premotor cortex contained similar amounts of dol, comprising approximately 8-9.5% of the total lipid weight. Interestingly, the corpus callosum contains substantially lower quantities of both dol and dol-CA compared to the other regions--less than 4% dol relative to the total lipid weight. Oxidized and reduced dolichol-related species were identified and determined to be region-dependent. (literal)

Prodotto di

• Invecchiamento e malattie neurodegenerative (ME.P02.018.001) (Modulo)

Autore CNR

• CHIARA BELLEI (Unità di personale interno)
• LUIGI ZECCA (Persona)
• FABIO ANDREA ZUCCA (Unità di personale interno)

Incoming links:

Autore CNR di

• LUIGI ZECCA (Persona)
• FABIO ANDREA ZUCCA (Unità di personale interno)
• CHIARA BELLEI (Unità di personale interno)

Prodotto

• Invecchiamento e malattie neurodegenerative (ME.P02.018.001) (Modulo)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• Archives of biochemistry and biophysics (Rivista)