http://www.cnr.it/ontology/cnr/individuo/prodotto/ID56061
Deep brain stimulation of the pedunculopontine tegmentum and subthalamic nucleus Effects on gait in Parkinson's disease (Articolo in rivista)
- Type
- Label
- Deep brain stimulation of the pedunculopontine tegmentum and subthalamic nucleus Effects on gait in Parkinson's disease (Articolo in rivista) (literal)
- Anno
- 2010-01-01T00:00:00+01:00 (literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi
- 10.1016/j.gaitpost.2010.07.012 (literal)
- Alternative label
Peppe A, Pierantozzi M, Chiavalon C, Marchetti F, Caltagirone C, Musicco M, Stanzione P, Stefani A. (2010)
Deep brain stimulation of the pedunculopontine tegmentum and subthalamic nucleus Effects on gait in Parkinson's disease
in Gait & posture
(literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
- Peppe A, Pierantozzi M, Chiavalon C, Marchetti F, Caltagirone C, Musicco M, Stanzione P, Stefani A. (literal)
- Pagina inizio
- Pagina fine
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume
- Rivista
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo
- Note
- ISI Web of Science (WOS) (literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
- I.R.C.C.S, Santa Lucia Foundation, Via Ardeatina 309, 00179 Rome, Italy; Department of Neuroscience, University of Rome ''Tor Vergata'', Rome, Italy; Institute of Biomedical Technology, National Research Council, Segrate, Milan, Italy (literal)
- Titolo
- Deep brain stimulation of the pedunculopontine tegmentum and subthalamic nucleus Effects on gait in Parkinson's disease (literal)
- Abstract
- Objective: This study examines the effects of subthalamic nucleus (STN) deep brain stimulation (DBS)
and pedunculopontine tegmentum (PPTg) DBS in advanced Parkinson's disease using gait analysis.
Methods: Five people underwent bilateral DBS in both the STN and PPTg. Gait analysis was performed
one year after neurosurgery using an optoelectronic system. The effects of DBS (STN, PPTg and
STN + PPTg) were studied in two clinical conditions: without (Off) and during (On) antiparkinsonian
therapy.
Results: PPTg and STN DBS were associated with changes in spatio-temporal and kinematics variables.
Conclusions: Although experimental data cannot be generalized widely due to the small sample, PPTg
DBS appears to affect the neuronal circuits subserving gait.
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