HmtDB, a human mitochondrial genomic resource based on variability studies supporting population genetics and biomedical research. (Articolo in rivista)

Type

• Prodotto della ricerca (Classe)
• Articolo in rivista (Classe)

Label

• HmtDB, a human mitochondrial genomic resource based on variability studies supporting population genetics and biomedical research. (Articolo in rivista) (literal)

Anno

• 2005-01-01T00:00:00+01:00 (literal)

Alternative label

• Attimonelli M, Accetturo M, Santamaria M, Lascaro D, Scioscia G, Pappadà G, Russo L, Zanchetta L, Tommaseo-Ponzetta M (2005)
  HmtDB, a human mitochondrial genomic resource based on variability studies supporting population genetics and biomedical research.
  in BMC bioinformatics
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• Attimonelli M, Accetturo M, Santamaria M, Lascaro D, Scioscia G, Pappadà G, Russo L, Zanchetta L, Tommaseo-Ponzetta M (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 6 (literal)

Rivista

• BMC bioinformatics (Rivista)

Note

• ISI Web of Science (WOS) (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• Marcella Attimonelli(1) Matteo Accetturo(1) Monica Santamaria(1)(4) Daniela Lascaro(1) Gaetano Scioscia(2) Graziano Pappadà(2) Luigi Russo(2) Luigi Zanchetta(2) and Mila Tommaseo-Ponzetta(3) (1)Dipartimento di Biochimica e Biologia Molecolare, Università di Bari, Via E. Orabona 4, 70126 Bari (Italy) (2)Java Technology Center, IBM Semea Sud, Via Tridente 42/14, 70125 Bari (Italy) (3)Dipartimento di Zoologia, Università di Bari, Via E. Orabona 4, 70126 Bari (Italy) (4)CNR - Istituto di Tecnologie Biomediche - Sede di Bari Via Amendola 122/D, 70126 Bari (literal)

Titolo

• HmtDB, a human mitochondrial genomic resource based on variability studies supporting population genetics and biomedical research. (literal)

Abstract

• BACKGROUND: Population genetics studies based on the analysis of mtDNA and mitochondrial disease studies have produced a huge quantity of sequence data and related information. These data are at present worldwide distributed in differently organised databases and web sites not well integrated among them. RESULTS: HmtDB is a well-integrated web-based human mitochondrial bioinformatic resource aimed at supporting population genetics and mitochondrial disease studies, thanks to a new approach based on site-specific nucleotide and aminoacid variability estimation. HmtDB consists of a database of Human Mitochondrial Genomes, annotated with population data, and a set of bioinformatic tools, able to produce site-specific variability data and to automatically characterize newly sequenced human mitochondrial genomes. A query system for the retrieval of genomes and a web submission tool for the annotation of new genomes have been designed and will soon be implemented. CONCLUSION: The HmtDB project will contribute towards completing and/or refining haplogroup classification and revealing the real pathogenic potential of mitochondrial mutations, on the basis of variability estimation. (literal)

Prodotto di

• Biodiversità Molecolare (SV.P17.006.001) (Modulo)

Autore CNR

• MONICA SANTAMARIA (Persona)

Insieme di parole chiave

• Keywords of "HmtDB, a human mitochondrial genomic resource based on variability studies supporting population genetics and biomedical research." (Insieme di parole chiave)

Incoming links:

Autore CNR di

• MONICA SANTAMARIA (Persona)

Prodotto

• Biodiversità Molecolare (SV.P17.006.001) (Modulo)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• BMC bioinformatics (Rivista)

Insieme di parole chiave di

• Keywords of "HmtDB, a human mitochondrial genomic resource based on variability studies supporting population genetics and biomedical research." (Insieme di parole chiave)