Gene analogue finder: a GRID solution for finding functionally analogous gene products. (Articolo in rivista)

Type
Label
  • Gene analogue finder: a GRID solution for finding functionally analogous gene products. (Articolo in rivista) (literal)
Anno
  • 2007-01-01T00:00:00+01:00 (literal)
Alternative label
  • Tulipano A, Donvito G, Licciulli F, Maggi G, Gisel A (2007)
    Gene analogue finder: a GRID solution for finding functionally analogous gene products.
    in BMC bioinformatics
    (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
  • Tulipano A, Donvito G, Licciulli F, Maggi G, Gisel A (literal)
Pagina inizio
  • 329 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume
  • 8 (literal)
Rivista
Note
  • ISI Web of Science (WOS) (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
  • Angelica Tulipano,#1,2 Giacinto Donvito,#2 Flavio Licciulli,3 Giorgio Maggi,1,2 and Andreas Gisel3 1Dipartimento Interateneo di Fisica, Università e Politecnico di Bari, via Amendola 173, 70126 Bari Italy 2INFN Bari, Via Amendola 173, Bari, Italy 3Istituto di Tecnologie Biomediche, CNR, Via Amendola 122/D, Bari, Italy (literal)
Titolo
  • Gene analogue finder: a GRID solution for finding functionally analogous gene products. (literal)
Abstract
  • To date more than 2,1 million gene products from more than 100000 different species have been described specifying their function, the processes they are involved in and their cellular localization using a very well defined and structured vocabulary, the gene ontology (GO). Such vast, well defined knowledge opens the possibility of compare gene products at the level of functionality, finding gene products which have a similar function or are involved in similar biological processes without relying on the conventional sequence similarity approach. Comparisons within such a large space of knowledge are highly data and computing intensive. For this reason this project was based upon the use of the computational GRID, a technology offering large computing and storage resources. RESULTS: We have developed a tool, GENe AnaloGue FINdEr (ENGINE) that parallelizes the search process and distributes the calculation and data over the computational GRID, splitting the process into many sub-processes and joining the calculation and the data on the same machine and therefore completing the whole search in about 3 days instead of occupying one single machine for more than 5 CPU years. The results (literal)
Prodotto di
Autore CNR

Incoming links:


Autore CNR di
Prodotto
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi
data.CNR.it