Molecular evolution of the Molecular evolution of the neurotrophin family members and their Trk receptors (Articolo in rivista)

Type

• Articolo in rivista (Classe)
• Prodotto della ricerca (Classe)

Label

• Molecular evolution of the Molecular evolution of the neurotrophin family members and their Trk receptors (Articolo in rivista) (literal)

Anno

• 2007-01-01T00:00:00+01:00 (literal)

Alternative label

• Lanave, C., Colangelo, A.M., Saccone C. and L. Alberghina. (2007)
  Molecular evolution of the Molecular evolution of the neurotrophin family members and their Trk receptors
  in Gene (Amst.)
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• Lanave, C., Colangelo, A.M., Saccone C. and L. Alberghina. (literal)

Pagina inizio

• 1 (literal)

Pagina fine

• 12 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 394 (literal)

Rivista

• Gene (Rivista)

Note

• ISI Web of Science (WOS) (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• Cecilia Lanave (a), Anna Maria Colangelo (b), Cecilia Saccone (a) (c), and Lilia Alberghina (b). (a) Institute for Biomedical Technologies, ITB-CNR, Bari, Italy (b) Laboratory of Neuroscience “R. Levi-Montalcini”, Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milano, Italy (c) Department of Biochemistry and Molecular Biology, University of Bari, Bari, Italy (literal)

Titolo

• Molecular evolution of the Molecular evolution of the neurotrophin family members and their Trk receptors (literal)

Abstract

• The study of the mechanisms underlying the coevolution processes of these gene families and how they correlate with the increased complexity of the vertebrate nervous system. In order to improve our current knowledge of the molecular evolution of neurotrophins and receptors, we have collected all information available in the literature and analyzed the genome database for each of them. Statistical analysis of aminoacid and nucleotide sequences of the neurotrophin and Trk family genes was applied to both complete genes and mature sequences, and different phylogenetic methods were used to compare aminoacid and nucleotide sequences variability among the different species. All collected data favor a model in which several rounds of genome duplications might have facilitated the generation of the many different neurotrophins and the acquisition of specific different functions correlated with the increased complexity of the vertebrate nervous system during evolution. We report findings that refine the structure of the evolutionary trees for neurotrophins and Trk receptors families, indicate different rates of evolution for each member of the two families. (literal)

Prodotto di

• Biodiversità Molecolare (SV.P17.006.001) (Modulo)

Autore CNR

• CECILIA SACCONE (Persona)
• CECILIA LANAVE (Persona)

Incoming links:

Autore CNR di

• CECILIA LANAVE (Persona)
• CECILIA SACCONE (Persona)

Prodotto

• Biodiversità Molecolare (SV.P17.006.001) (Modulo)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• Gene (Rivista)