http://www.cnr.it/ontology/cnr/individuo/prodotto/ID54294
Differential expression of nuclear lamins in normal and cancerous prostate tissues (Articolo in rivista)
- Type
- Label
- Differential expression of nuclear lamins in normal and cancerous prostate tissues (Articolo in rivista) (literal)
- Anno
- 2006-01-01T00:00:00+01:00 (literal)
- Alternative label
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
- Coradeghini R.; Barboro P.; Rubagotti A.; Boccardo F.; Parodi S.; Carmignani G.; D'Arrigo C.; Patrone E.; Balbi C. (literal)
- Pagina inizio
- Pagina fine
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume
- Rivista
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo
- Note
- Scopu (literal)
- ISI Web of Science (WOS) (literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
- D'Arrigo C., Patrone E.: CNR, ISMAC-GE
Coradeghini R., Barboro P., Rubagotti A., Boccardo F., Parodi S., Carmignani G., Balbi C.: Istituto Nazionale per la ricerca sul cancro (IST), Genova (literal)
- Titolo
- Differential expression of nuclear lamins in normal and cancerous prostate tissues (literal)
- Abstract
- The process of carcinogenesis is characterized by definite changes in the protein composition of the nuclear matrix. We have recently found that lamins form, in addition to the nuclear lamina, an intranuclear web of thin fibrils. This finding prompted us to address the question of whether changes in the expression of lamins occur in the course of tumor development. In prostate cancer, lamin B undergoes a significant increase; interestingly, its nuclear content strongly correlates with tumor differentiation. Moreover, all the lamins show reproducible alterations in the distribution of the isoelectric variants, suggesting that dephosphorylation events could trigger changes in the pattern of gene expression by inducing structural rearrangements of the nuclear scaffold. (literal)
- Prodotto di
- Autore CNR
- Insieme di parole chiave
Incoming links:
- Prodotto
- Autore CNR di
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi
- Insieme di parole chiave di