Molecular characterization of a,b-poly[(N-hydroxyethyl)-DL-aspartamide] derivatives as potential self-assembling copolymers forming polymeric micelles (Articolo in rivista)

Type
Label
  • Molecular characterization of a,b-poly[(N-hydroxyethyl)-DL-aspartamide] derivatives as potential self-assembling copolymers forming polymeric micelles (Articolo in rivista) (literal)
Anno
  • 2003-01-01T00:00:00+01:00 (literal)
Alternative label
  • Mendichi R., Giacometti Schieroni A., Cavallaro G., Licciardi M., Giammona G. (2003)
    Molecular characterization of a,b-poly[(N-hydroxyethyl)-DL-aspartamide] derivatives as potential self-assembling copolymers forming polymeric micelles
    (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
  • Mendichi R., Giacometti Schieroni A., Cavallaro G., Licciardi M., Giammona G. (literal)
Pagina inizio
  • 4871 (literal)
Pagina fine
  • 4879 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume
  • 44 (literal)
Note
  • ISI Web of Science (WOS) (literal)
Titolo
  • Molecular characterization of a,b-poly[(N-hydroxyethyl)-DL-aspartamide] derivatives as potential self-assembling copolymers forming polymeric micelles (literal)
Abstract
  • A family of graft copolymers derivatives obtained from a,b-Poly(N-2-hydroxyethyl)-DL-aspartamide (PHEA) have been studied as potential self-assembling macromolecules forming stable polymeric micelles at low critical micellar concentration. These polymers are obtained grafting on PHEA poly(ethylene glycol) (PEG) with molar mass of 5 Kg/mol (PHEA-PEG), hexadecylamine (PHEA-C16) or both moieties (PHEA-PEG-C16). Preliminary the PHEA derivatives was characterized by a multi-angle light scattering photometer on line to a size exclusion chromatography system in obtaining the molar mass distribution of the polymers. In addition, to investigate the capacity to form micellar aggregates in aqueous medium the multi-angle light scattering photometer was used in off-line batch mode in obtaining molar mass and dimension of the polymeric aggregates. (literal)
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