Report from the killer immunoglobulin-like receptor (KIR) anthropology component of the 15th International Histocompatibility Workshop: worldwide variation in the KIR loci and further evidence for the co-evolution of KIR and HLA. (Articolo in rivista)

Type
Label
  • Report from the killer immunoglobulin-like receptor (KIR) anthropology component of the 15th International Histocompatibility Workshop: worldwide variation in the KIR loci and further evidence for the co-evolution of KIR and HLA. (Articolo in rivista) (literal)
Anno
  • 2010-01-01T00:00:00+01:00 (literal)
Alternative label
  • Hollenbach JA1; Meenagh A2; Sleator C2; Alaez C3; Bengoche M4; Canossi A5; Contreras G3; Creary L6; Evseeva I7; Gorodezky C3; Hardie RA8; Karlsen TH9; Lie B9; Luo M8; Martinetti M10; Navarette C6; de Oliveira DC11; Ozzella G5; Pasi A10; Pavlova E12; Pinto S13; Porto LC11; Santos P13; Slavcev A12, Srinak D14, Tavoularis S15, Tonks S16, Trachtenberg E1, Vejbaesya S14;Middleton D17 (2010)
    Report from the killer immunoglobulin-like receptor (KIR) anthropology component of the 15th International Histocompatibility Workshop: worldwide variation in the KIR loci and further evidence for the co-evolution of KIR and HLA.
    in Tissue antigens
    (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
  • Hollenbach JA1; Meenagh A2; Sleator C2; Alaez C3; Bengoche M4; Canossi A5; Contreras G3; Creary L6; Evseeva I7; Gorodezky C3; Hardie RA8; Karlsen TH9; Lie B9; Luo M8; Martinetti M10; Navarette C6; de Oliveira DC11; Ozzella G5; Pasi A10; Pavlova E12; Pinto S13; Porto LC11; Santos P13; Slavcev A12, Srinak D14, Tavoularis S15, Tonks S16, Trachtenberg E1, Vejbaesya S14;Middleton D17 (literal)
Pagina inizio
  • 9 (literal)
Pagina fine
  • 17 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume
  • 76 (literal)
Rivista
Note
  • Scopu (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
  • 1 Center for Genetics, Children's Hospital Oakland Research Institute, Oakland, CA USA; 2 Northern Ireland Histocompatibility and Immunogenetics Laboratory Belfast, Northern Ireland; 3 Department of Immunology and Immunogenetics, InDRE, Secretary of Health, M´ exico DF, Mexico; 4 Immunogenetics and Histocompatibility Laboratory, Instituto Nacional de Donaci ´on y Trasplante (INDT), Uruguay; 5 CNR Institute of Organ Transplants and Immunocytology, L'Aquila, Italy; 6 Histocompatibility and Immunogenetics Research Group NHSBT, Colindale Centre, London, UK; 7 Department of Clinical Pharmacology, University of Oxford, Oxford, UK; 8 Department of Medical Microbiology, University of Manitoba, Manitoba, Canada; 9 Institute of Immunology, Rikshospitalet, Oslo University Hospital, Oslo, Norway; 10 Immunogenetics Laboratory, Immunohaematology and Transfusion Center, IRCCS Foundation Policlinico San Matteo, Pavia, Italy; 11 Histocompatibility and Cryopreservation Laboratory, Rio de Janeiro State University, Rio de Janeiro, Brazil; 12 Department of Immunogenetics, Institute for Clinical and Experimental Medicine (IKEM), Prague, Czech Republic; 13 Functional Genomics Laboratory, Centre for Histocompatibility of the Centre, Coimbra, Portugal; 14 Department of Transfusion Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand; 15 Canadian Blood Services, Head Office, HLA Laboratory, Ottawa, Canada; 16 Cancer and Immunogenetics Laboratory, CR-UK Weatherall Institute of Molecular Medicine, Oxford, UK; 17 Transplant Immunology, Royal Liverpool Hospital and School of Immunity and Host Defence, University of Liverpool, Liverpool, UK (literal)
Titolo
  • Report from the killer immunoglobulin-like receptor (KIR) anthropology component of the 15th International Histocompatibility Workshop: worldwide variation in the KIR loci and further evidence for the co-evolution of KIR and HLA. (literal)
Abstract
  • The killer immunoglobulin-like receptor (KIR) anthropology component of the 15th International Histocompatibility Workshop (IHIWS) sought to explore worldwide population variation in the KIR loci, and to examine the relationship between KIR genes and their human leukocyte antigen (HLA) ligands. Fifteen laboratories submitted KIR genotype and HLA ligand data in 27 populations from six broad ethnic groups. Data were analyzed for correlations between the frequencies of KIR and their known HLA ligands. In addition, allelic typing was performed for KIR2DL2 and 3DL1 in a subset of populations. Strong and significant correlations were observed between KIR2DL2, 2DL3 genotype frequencies and the frequency of their ligand, HLA-C1. In contrast, only weak associations were seen for 3DL1, 3DS1 and the HLA-Bw4 ligand. Although some aspects of the correlations observed here differ from those reported in other populations, these data provide additional evidence of linked evolutionary histories for some KIR and HLA loci. Investigation of allele-level variation for the B haplotype locus KIR 2DL2 showed that two alleles, *001 and *003, predominate in all populations in this study. Much more allelic variation was observed for the A haplotype locus 3DL1, with several alleles observed at moderate frequencies and extensive variation observed between populations. (literal)
Prodotto di
Autore CNR

Incoming links:


Autore CNR di
Prodotto
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi
data.CNR.it