Investigation on the possible relationship existing between HLA-DR gene and attention deficit hyperactivity disorder and/or mental retardation. (Articolo in rivista)

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  • Investigation on the possible relationship existing between HLA-DR gene and attention deficit hyperactivity disorder and/or mental retardation. (Articolo in rivista) (literal)
Anno
  • 2008-01-01T00:00:00+01:00 (literal)
Alternative label
  • Aureli A; Sebastiani P; Del Beato T; Marimpietri A1; Melillo V1; Sechi E1; Di Loreto S. (2008)
    Investigation on the possible relationship existing between HLA-DR gene and attention deficit hyperactivity disorder and/or mental retardation.
    in International journal of immunopathology and pharmacology; Università di Chieti, Chieti (Italia)
    (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
  • Aureli A; Sebastiani P; Del Beato T; Marimpietri A1; Melillo V1; Sechi E1; Di Loreto S. (literal)
Pagina inizio
  • 985 (literal)
Pagina fine
  • 991 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume
  • 21 (literal)
Rivista
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  • 6 (literal)
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  • 4 (literal)
Note
  • Google Scholar (literal)
  • copus (literal)
  • ISI Web of Science (WOS) (literal)
  • PubMe (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
  • CNR ITOI Institute for organ transplantation and immunocytology, L'Aquila, Italy; 1 Childhood and Adolescence Neuropsychiatric Clinic; University of L'Aquila - ASL n. 4. L'Aquila, Italy. (literal)
Titolo
  • Investigation on the possible relationship existing between HLA-DR gene and attention deficit hyperactivity disorder and/or mental retardation. (literal)
Abstract
  • This study examines the possible relationship existing between the HLA-DR gene and attention deficit hyperactivity disorder (ADHD) and/or mental retardation (MR). The diagnosis of ADHD and mental retardation were established through clinical interviews with the parents, children and teachers, according to the criteria in DSM-IV. HLA-DRB1 genotyping was performed both by polymerase chain reaction-sequence specific primers (PCR-SSP) and by sequence based typing (SBT) in a cohort of 81 affected children and a sample of 100 healthy controls. Here, we report a positive association of HLA-DR4 with ADHD but not with MR. The study adds confirmation to the role of the HLA-DRB1 in the etiology of some types of childhood neuropsychiatric illnesses. (literal)
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