Genotoxic properties of extremely low frequency electromagnetic fields (Articolo in rivista)

Type
Label
  • Genotoxic properties of extremely low frequency electromagnetic fields (Articolo in rivista) (literal)
Anno
  • 2010-01-01T00:00:00+01:00 (literal)
Alternative label
  • Udroiu I. (1), Giuliani L. (1), Ieradi L.A. (2010)
    Genotoxic properties of extremely low frequency electromagnetic fields
    in European journal of oncology
    (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
  • Udroiu I. (1), Giuliani L. (1), Ieradi L.A. (literal)
Pagina inizio
  • 123 (literal)
Pagina fine
  • 134 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume
  • 5 (literal)
Rivista
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#note
  • Udroiu I., Giuliani L., Ieradi L.A. (2010). Genotoxic properties of extremely low frequency electromagnetic fields. European Journal of Oncology, 5: 123-134 (literal)
Note
  • ISI Web of Science (WOS) (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
  • (1) National Institute for Prevention and Safety at Work, Rome, Italy (literal)
Titolo
  • Genotoxic properties of extremely low frequency electromagnetic fields (literal)
Abstract
  • Many authors have examined the genotoxic properties of magnetic fields. Some studies detected increases in micronuclei frequencies and chromosomal aberrations in samples taken from individuals professionally exposed, such as photocopying machine workers, power-line operators and railwaymen. More abundantly, laboratory studies validated the hypothesis that magnetic fields would induce DNA damage. Genotoxicity studies included detection of Sister Chromatid Exchange (SCE), Chromosomal Aberrations (CA), presence of 8- hydroxy-2’-deoxyguanosine, the alkaline single cell gel electrophoresis (Comet test) and the Micronucleus test. Among genotoxicity assays, one of the most popular is the micronucleus test, because of its simplicity, sensitivity and reliability. Micronuclei are nuclear remains produced during mitosis (or meiosis) when a chromosome fragment or an entire chromosome fails to migrate with one of the two daughter nuclei formed. Basically, this assay consists in the observation of the variations of the frequencies of micronucleated cells. Investigations have been conducted both with in vitro and in vivo exposure. Several works denied the hypothesis that Extremely Low Frequency (ELF) magnetic fields have genotoxic properties, while other studies have detected positive results only in conditions of co-exposure with other mutagenic agents, such as static magnetic fields, X and gamma rays, benzopyrene, aflatoxine and vinblastine. These results led to the hypothesis that ELF magnetic fields are able to enhance, but not to start, a mutagenic event. This statement could be strengthened when you consider the combined action of ELF and static magnetic fields. In the last years, however, an increasing number of works detected genotoxic properties of ELF magnetic fields, both with in vivo and in vitro exposure. (literal)
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