Crystallization process of carbonate substituted hydroxyapatite nanoparticles in toothpastes upon physiological conditions: an in situ time-resolved X-ray diffraction study (Articolo in rivista)

Type
Label
  • Crystallization process of carbonate substituted hydroxyapatite nanoparticles in toothpastes upon physiological conditions: an in situ time-resolved X-ray diffraction study (Articolo in rivista) (literal)
Anno
  • 2010-01-01T00:00:00+01:00 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi
  • 10.1007/s10856-009-3905-z (literal)
Alternative label
  • Generosi A. (1); Rau J.V. (1); Rossi Albertini V. (1); Paci B. (1); (2010)
    Crystallization process of carbonate substituted hydroxyapatite nanoparticles in toothpastes upon physiological conditions: an in situ time-resolved X-ray diffraction study
    in Journal of materials science. Materials in medicine
    (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
  • Generosi A. (1); Rau J.V. (1); Rossi Albertini V. (1); Paci B. (1); (literal)
Pagina inizio
  • 445 (literal)
Pagina fine
  • 450 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume
  • 21 (literal)
Rivista
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#note
  • http://dx.doi.org/10.1007/s10856-009-3905-z (literal)
Note
  • ISI Web of Science (WOS) (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
  • (1) Istituto di Struttura della Materia, CNR, Italy (literal)
Titolo
  • Crystallization process of carbonate substituted hydroxyapatite nanoparticles in toothpastes upon physiological conditions: an in situ time-resolved X-ray diffraction study (literal)
Abstract
  • The crystallization process in recently developed toothpastes, containing nanoparticles of carbonate substituted hydroxyapatite (nano-CHA), was investigated. For this purpose, the non-conventional Energy Dispersive X-Ray Diffraction technique, that demonstrated to be a powerful tool to follow in situ phase transformations, was applied, for the first time, to products of pharmaceutical-cosmetic interest. Two types of toothpastes, containing 15 and 20 wt% of nano-CHA, respectively, have been studied. It was observed that, after mixing the toothpastes with water and saliva in order to reproduce in vivo conditions, a crystallization of nano-CHA takes place. Such process occurs in a characteristic time of (22 ± 1) min for the toothpaste containing 15 wt% of nano-CHA and of (3.9 ± 0.5) min for the one containing 20% of nano-CHA. For both toothpastes, a 10% increase in grain dimensions was observed over an average characteristic time of (55 ± 5) min. (literal)
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