http://www.cnr.it/ontology/cnr/individuo/prodotto/ID51595
Identification of plasma haptoglobin forms which loosely bind hemoglobin. (Articolo in rivista)
- Type
- Label
- Identification of plasma haptoglobin forms which loosely bind hemoglobin. (Articolo in rivista) (literal)
- Anno
- 2011-01-01T00:00:00+01:00 (literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi
- 10.1515/BC.2011.033 (literal)
- Alternative label
Spagnuolo MS, Cigliano L, Maresca B, Pugliese CR, Abrescia P. (2011)
Identification of plasma haptoglobin forms which loosely bind hemoglobin.
in Biological chemistry (Print); WALTER DE GRUYTER & CO, Berlin (Germania)
(literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
- Spagnuolo MS, Cigliano L, Maresca B, Pugliese CR, Abrescia P. (literal)
- Pagina inizio
- Pagina fine
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume
- Rivista
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#pagineTotali
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo
- Note
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
- Istituto per il Sistema Produzione Animale in Ambiente Mediterraneo, Consiglio Nazionale delle Ricerche, I-80147 Napoli, Italy. (literal)
- Titolo
- Identification of plasma haptoglobin forms which loosely bind hemoglobin. (literal)
- Abstract
- Abstract Haptoglobin (Hpt) is known to capture circulating free hemoglobin (Hb) and bind apolipoprotein (Apo) A-I or E. Here, we report that Hb can be tightly bound by most of Hpt molecules (TB-Hpt, 80%), whereas loosely bound by a minor part of them (LB-Hpt, 20%). LB-Hpt amount was significantly increased (over 60%) in patients with acute coronary syndrome. LB-Hpt bound ApoA-I and ApoE less efficiently than TB-Hpt (8- and 4-fold less, respectively) and did not affect their activity of stimulating the enzyme lecithin-cholesterol acyltransferase. LB-Hpt and TB-Hpt displayed comparable levels of nitrotyrosine residues, but differences in glycan chains. Changes in LB-Hpt level might be associated with changes in Hpt functions. (literal)
- Editore
- Prodotto di
- Autore CNR
Incoming links:
- Autore CNR di
- Prodotto
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi
- Editore di