Transcription regulation by the adaptor protein fe65 and the nucleosome assembly factor set (Articolo in rivista)

Type

• Articolo in rivista (Classe)
• Prodotto della ricerca (Classe)

Label

• Transcription regulation by the adaptor protein fe65 and the nucleosome assembly factor set (Articolo in rivista) (literal)

Anno

• 2005-01-01T00:00:00+01:00 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi

• 10.1038/sj.embor.7400309 (literal)

Alternative label

• Telese F, Bruni P, Donizetti A, D'Ambrosio C, Scaloni A, Zambiano N, Rosenfeld MG, Russo T (2005)
  Transcription regulation by the adaptor protein fe65 and the nucleosome assembly factor set
  in EMBO reports (Print)
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• Telese F, Bruni P, Donizetti A, D'Ambrosio C, Scaloni A, Zambiano N, Rosenfeld MG, Russo T (literal)

Pagina inizio

• 77 (literal)

Pagina fine

• 82 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 6 (literal)

Rivista

• EMBO reports (Rivista)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo

• 1 (literal)

Note

• ISI Web of Science (WOS) (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• Univ Naples Federico II, Dept Biochim & Biotechnol Med, CEINGE Biotecnol Avanzate, I-80131 Naples, Italy Univ Calif San Diego, Howard Hughes Med Inst, La Jolla, CA 92093 USA CNR, ISPAAM, Prote & Mass Spectrometry Lab, I-80147 Naples, Italy (literal)

Titolo

• Transcription regulation by the adaptor protein fe65 and the nucleosome assembly factor set (literal)

Abstract

• Fe65 protein interacts with the cytosolic domain of the amyloid precursor APP. Its possible involvement in gene regulation is suggested by numerous observations, including those demonstrating that it activates transcription. Here, we show that the Fe65 transcription activation domain overlaps with the WW domain of Fe65 and binds to the nucleosome assembly factor SET. This protein is required for the Fe65-mediated transactivation of a reporter gene. Two-step chromatin immunoprecipitation experiments demonstrate that a complex including Fe65/AICD/Tip60 and SET is associated with the KAI1 gene promoter. Suppression of SET levels by RNA interference shows that this protein is required for full levels of basal transcription of the KAI1 gene. These results further support the function of Fe65 and APP in gene regulation and show a new role for the SET factor. (literal)

Prodotto di

• Institute for animal production system in mediterranean environment (ISPAAM) (Istituto)
• Metodologie genomiche e proteomiche applicate al sistema zootecnico ed agroindustriale (AG.P01.015.001) (Modulo)

Autore CNR

• ANDREA SCALONI (Persona)
• CHIARA D'AMBROSIO (Unità di personale esterno)

Insieme di parole chiave

• Keywords of "Transcription regulation by the adaptor protein fe65 and the nucleosome assembly factor set" (Insieme di parole chiave)

Incoming links:

Autore CNR di

• ANDREA SCALONI (Persona)
• CHIARA D'AMBROSIO (Unità di personale esterno)

Prodotto

• Institute for animal production system in mediterranean environment (ISPAAM) (Istituto)
• Metodologie genomiche e proteomiche applicate al sistema zootecnico ed agroindustriale (AG.P01.015.001) (Modulo)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• EMBO reports (Rivista)

Insieme di parole chiave di

• Keywords of "Transcription regulation by the adaptor protein fe65 and the nucleosome assembly factor set" (Insieme di parole chiave)