Proteomic analysis of liver tissues subjected to early ischemia/reperfusion injury during orthotopic liver transplanation (Articolo in rivista)

Type

• Articolo in rivista (Classe)
• Prodotto della ricerca (Classe)

Label

• Proteomic analysis of liver tissues subjected to early ischemia/reperfusion injury during orthotopic liver transplanation (Articolo in rivista) (literal)

Anno

• 2006-01-01T00:00:00+01:00 (literal)

Alternative label

• Vascotto C, Cesaratto L, D’Ambrosio C, Scaloni A, Avellini C, Baccarani U, Paron I, Adani GL, Tiribelli C, Quadrifoglio F, Tell G (2006)
  Proteomic analysis of liver tissues subjected to early ischemia/reperfusion injury during orthotopic liver transplanation
  in Proteomics (Weinh., Print)
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• Vascotto C, Cesaratto L, D’Ambrosio C, Scaloni A, Avellini C, Baccarani U, Paron I, Adani GL, Tiribelli C, Quadrifoglio F, Tell G (literal)

Pagina inizio

• 3455 (literal)

Pagina fine

• 3465 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 6 (literal)

Rivista

• Proteomics (Rivista)

Note

• ISI Web of Science (WOS) (literal)

Titolo

• Proteomic analysis of liver tissues subjected to early ischemia/reperfusion injury during orthotopic liver transplanation (literal)

Abstract

• Knowledge of early molecular events occurring upon ischemia/reperfusion (I/R) during liver transplantation (LT) is of great importance to improve the therapeutic intervention of surgical treatment. However, nowadays, few data are available on early protein targets of I/R injury. To identify these proteins, we used a differential proteomics approach in the characterization human liver biopsies during I/R upon LT. Analyses were performed on nine donor livers during LT. By using 2-DE and MALDI-TOF MS, we identified 36 proteins which resulted significantly altered upon I/R injury. The majority of these proteins are functionally involved in lipid and energy metabolism, in different metabolic pathways, in redox signalling and in oxidative-stress response. Our data represent the first global approach in the study of I/R injury in liver. (literal)

Prodotto di

• Caratterizzazione, valorizzazione e sostenibilità di specie di rilevante interesse zootecnico mediante metodologie classiche e innovative (AG.P04.014.001) (Modulo)
• Institute for animal production system in mediterranean environment (ISPAAM) (Istituto)

Autore CNR

• CHIARA D'AMBROSIO (Unità di personale esterno)
• ANDREA SCALONI (Persona)

Incoming links:

Autore CNR di

• ANDREA SCALONI (Persona)
• CHIARA D'AMBROSIO (Unità di personale esterno)

Prodotto

• Institute for animal production system in mediterranean environment (ISPAAM) (Istituto)
• Caratterizzazione, valorizzazione e sostenibilità di specie di rilevante interesse zootecnico mediante metodologie classiche e innovative (AG.P04.014.001) (Modulo)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• Proteomics (Rivista)